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| − | [[Category:Metabolite]] | + | [[Category:Reaction]] |
| − | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NAD NAD] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-13307 RXN-13307] == |
| − | * smiles:
| + | * direction: |
| − | ** C1(C(=CC=C[N+]=1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O)
| + | ** LEFT-TO-RIGHT |
| − | * inchi key: | + | * ec number: |
| − | ** InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-M | + | ** [http://enzyme.expasy.org/EC/1.3.1.93 EC-1.3.1.93] |
| − | * common name: | + | |
| − | ** NAD+ | + | |
| − | * molecular weight:
| + | |
| − | ** 662.422
| + | |
| | * Synonym(s): | | * Synonym(s): |
| − | ** NAD+
| |
| − | ** beta-nicotinamide adenine dinucleotide
| |
| − | ** coenzyme I
| |
| − | ** diphosphopyridine nucleotide
| |
| − | ** diphosphopyridine nucleotide oxidized
| |
| − | ** nicotinamide adenine dinucleotide
| |
| − | ** nicotinamide adenine dinucleotide oxidized
| |
| − | ** NAD-oxidized
| |
| − | ** NAD-ox
| |
| − | ** DPN+
| |
| − | ** DPN-ox
| |
| − | ** DPN
| |
| − | ** β-nicotinamide adenine dinucleotide
| |
| − | ** NAD
| |
| − | ** β-NAD+
| |
| | | | |
| − | == Reaction(s) known to consume the compound == | + | == Reaction Formula == |
| − | * [[RXN-8001]] | + | * With identifiers: |
| − | * [[RXN-4142]] | + | ** 1 [[CPD-14281]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[NADPH]][c] '''=>''' 1 [[CPD-10279]][c] '''+''' 1 [[NADP]][c] |
| − | * [[THREODEHYD-RXN]] | + | * With common name(s): |
| − | * [[RXN-14249]]
| + | ** 1 trans-docos-2-enoyl-CoA[c] '''+''' 1 H+[c] '''+''' 1 NADPH[c] '''=>''' 1 docosanoyl-CoA[c] '''+''' 1 NADP+[c] |
| − | * [[RXN-12490]]
| + | |
| − | * [[RXN66-479]]
| + | == Genes associated with this reaction == |
| − | * [[RXN-17794]]
| + | == Pathways == |
| − | * [[RXN-17777]]
| + | * [[PWY-7036]], very long chain fatty acid biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7036 PWY-7036] |
| − | * [[RXN66-476-CPD-388/NAD/WATER//CPD-8462/NADH/PROTON.40.]]
| + | ** '''8''' reactions found over '''16''' reactions in the full pathway |
| − | * [[RXN-17790]]
| + | == Reconstruction information == |
| − | * [[RXN66-476-CPD-14719/NAD/WATER//CPD-7830/NADH/PROTON.42.]]
| + | * Category: [[gap-filling]] |
| − | * [[RXN-12705]]
| + | ** Source: [[gap-filling-gapfilling_solution_with_meneco_draft_medium]] |
| − | * [[NADPYROPHOSPHAT-RXN]]
| + | *** Tool: [[meneco]] |
| − | * [[1.8.1.4-RXN]]
| + | **** Comment: [[added for gapfilling]] |
| − | * [[RXN66-3]]
| + | |
| − | * [[RXN-17798]]
| + | |
| − | * [[PREPHENATEDEHYDROG-RXN]]
| + | |
| − | * [[RXN-905]]
| + | |
| − | * [[RXN-10715]]
| + | |
| − | * [[ISOCITRATE-DEHYDROGENASE-NAD+-RXN]]
| + | |
| − | * [[RXN-9758]]
| + | |
| − | * [[RXN-10912]]
| + | |
| − | * [[RXN-10917]]
| + | |
| − | * [[RXN-12507]]
| + | |
| − | * [[PYRUVDEH-RXN]]
| + | |
| − | * [[RXN-7682]]
| + | |
| − | * [[RXN-17808]]
| + | |
| − | * [[RXN-12750]]
| + | |
| − | * [[2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN]]
| + | |
| − | * [[RXN66-472]]
| + | |
| − | * [[PYRNUTRANSHYDROGEN-RXN]]
| + | |
| − | * [[RXN6666-5]]
| + | |
| − | * [[2OXOGLUTARATEDEH-RXN]]
| + | |
| − | * [[RXN-37]]
| + | |
| − | * [[RXN-7745]]
| + | |
| − | * [[OHACYL-COA-DEHYDROG-RXN]]
| + | |
| − | * [[NAD-KIN-RXN]]
| + | |
| − | * [[RXN-3443]]
| + | |
| − | * [[RXN66-342]]
| + | |
| − | * [[RXN-1884]]
| + | |
| − | * [[HISTALDEHYD-RXN]]
| + | |
| − | * [[RXN-10698]]
| + | |
| − | * [[RXN66-476]]
| + | |
| − | * [[RXN-12693]]
| + | |
| − | * [[RXN-17781]]
| + | |
| − | * [[RXN-14271]]
| + | |
| − | * [[RXN66-353]]
| + | |
| − | * [[1.1.1.39-RXN]]
| + | |
| − | * [[RXN-13158]]
| + | |
| − | * [[UGD-RXN]]
| + | |
| − | * [[ExchangeDeadEnd_NAD]] | + | |
| − | * [[RXN-10702]]
| + | |
| − | * [[RXN-10703]]
| + | |
| − | * [[RXN-10780]]
| + | |
| − | * [[RXN-10089]]
| + | |
| − | * [[RXN-12789]]
| + | |
| − | * [[ALDHDEHYDROG-RXN]]
| + | |
| − | * [[RXN0-1132]]
| + | |
| − | * [[RXN-9336]]
| + | |
| − | * [[RXN-17786]]
| + | |
| − | * [[2-KETO-ADIPATE-DEHYDROG-RXN]]
| + | |
| − | * [[3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN]]
| + | |
| − | * [[TransportSeed_NAD]]
| + | |
| − | * [[PYRIDOXAL-4-DEHYDROGENASE-RXN]]
| + | |
| − | * [[R222-RXN]]
| + | |
| − | * [[1.2.1.25-RXN]]
| + | |
| − | * [[RXN-13414]]
| + | |
| − | * [[RXN66-478]]
| + | |
| − | * [[RXN-11245]]
| + | |
| − | == Reaction(s) known to produce the compound ==
| + | |
| − | * [[RXN-11195]] | + | |
| − | * [[TRANS-RXN0-277]] | + | |
| − | * [[RXN-16632]]
| + | |
| − | * [[RXN-10062]]
| + | |
| − | * [[RXN-5424]]
| + | |
| − | * [[RXN-11478]]
| + | |
| − | * [[1.5.1.20-RXN]]
| + | |
| − | * [[RXN-3661]]
| + | |
| − | * [[RXN3O-4113]]
| + | |
| − | * [[DLACTDEHYDROGNAD-RXN]]
| + | |
| − | * [[RXN1G-488]]
| + | |
| − | * [[RXN1G-526]]
| + | |
| − | * [[RXN-9659]]
| + | |
| − | * [[RXN-9658]]
| + | |
| − | * [[RXN-10911]]
| + | |
| − | * [[TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10280/NAD//CPD-14282/NADH/PROTON.37.]]
| + | |
| − | * [[RXN-11482]]
| + | |
| − | * [[RXN-9635]]
| + | |
| − | * [[ENOYL-ACP-REDUCT-NADH-RXN]]
| + | |
| − | * [[RXN-10657]]
| + | |
| − | * [[RXN-7694]]
| + | |
| − | * [[1.1.1.8-RXN]]
| + | |
| − | * [[GLYCERATE-DEHYDROGENASE-RXN]]
| + | |
| − | * [[RXN-16628]]
| + | |
| − | * [[RXN1F-152]]
| + | |
| − | * [[RXN-16620]]
| + | |
| − | * [[RXN-7700]]
| + | |
| − | * [[RXN-16624]]
| + | |
| − | * [[FERRIC-CHELATE-REDUCTASE-RXN]]
| + | |
| − | * [[RXN-7706]]
| + | |
| − | * [[1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.]]
| + | |
| − | * [[TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10279/NAD//CPD-14281/NADH/PROTON.37.]]
| + | |
| − | * [[RXN0-2145]]
| + | |
| − | * [[RXN1G-395]]
| + | |
| − | * [[BIOMASS-RXN]]
| + | |
| − | * [[CYTOCHROME-B5-REDUCTASE-RXN]]
| + | |
| − | * [[1.6.5.4-RXN]]
| + | |
| − | * [[HOMOSERDEHYDROG-RXN-HOMO-SER/NAD//L-ASPARTATE-SEMIALDEHYDE/NADH/PROTON.51.]]
| + | |
| − | * [[RXN-9662]]
| + | |
| − | * [[RXN-9663]]
| + | |
| − | * [[RXN-9660]]
| + | |
| − | * [[RXN-9661]]
| + | |
| − | * [[RXN-9558]]
| + | |
| − | * [[RXN-12559]]
| + | |
| − | * [[RXN-12558]]
| + | |
| − | * [[RXN-12570]]
| + | |
| − | * [[RXN-5822]]
| + | |
| − | * [[RXN-9657]]
| + | |
| − | * [[RXN-13417]]
| + | |
| − | * [[RXN-10661]]
| + | |
| − | * [[TransportSeed_NAD]]
| + | |
| − | * [[ExchangeDeadEnd_NAD]]
| + | |
| − | * [[NAD-SYNTH-GLN-RXN]]
| + | |
| − | * [[RXN-10781]]
| + | |
| − | * [[RXN-12568-HEXANAL/CO-A/NAD//HEXANOYL-COA/NADH/PROTON.43.]]
| + | |
| − | == Reaction(s) of unknown directionality == | + | |
| − | * [[ExchangeSeed_NAD]] | + | |
| − | * [[NADH-DEHYDROG-A-RXN]]
| + | |
| − | * [[RXN-7719]]
| + | |
| − | * [[PHENDEHYD-RXN]]
| + | |
| − | * [[RXN0-901]]
| + | |
| − | * [[D-THREO-ALDOSE-1-DEHYDROGENASE-RXN]]
| + | |
| − | * [[RXN-7644]]
| + | |
| − | * [[RXN-7716]]
| + | |
| − | * [[LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-348/NAD/WATER//PALMITATE/NADH/PROTON.41.]]
| + | |
| − | * [[LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-7873/NAD/WATER//STEARIC_ACID/NADH/PROTON.45.]]
| + | |
| − | * [[IMP-DEHYDROG-RXN]]
| + | |
| − | * [[RXN-14280]]
| + | |
| − | * [[GLYCOLATE-REDUCTASE-RXN]] | + | |
| − | * [[HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN]] | + | |
| − | * [[HEXADECANOL-DEHYDROGENASE-RXN]]
| + | |
| − | * [[RXN-16654]] | + | |
| − | * [[NADH-DEHYDROGENASE-RXN]] | + | |
| − | * [[RXN-8629]] | + | |
| − | * [[RXN-12448]]
| + | |
| − | * [[RXN-11662]] | + | |
| − | * [[RXN-12303-PLASTOQUINONE-9/NADH/PROTON//CPD-12829/NAD.43.]] | + | |
| − | * [[ALCOHOL-DEHYDROG-GENERIC-RXN]] | + | |
| − | * [[L-IDITOL-2-DEHYDROGENASE-RXN]] | + | |
| − | * [[RXN-10915]] | + | |
| − | * [[GLUTAMATE-DEHYDROGENASE-RXN]] | + | |
| − | * [[RETINOL-DEHYDROGENASE-RXN]] | + | |
| − | * [[HISTOLDEHYD-RXN]]
| + | |
| − | * [[1.6.99.5-RXN-NADH/PLASTOQUINONE-9/PROTON//NAD/CPD-12829.43.]]
| + | |
| − | * [[RXN-9510]]
| + | |
| − | * [[MALATE-DEH-RXN]]
| + | |
| − | * [[2KETO-3METHYLVALERATE-RXN]]
| + | |
| − | * [[RXN-7657]]
| + | |
| − | * [[ALCOHOL-DEHYDROG-RXN]]
| + | |
| − | * [[RXN-161]]
| + | |
| − | * [[RXN-1302]]
| + | |
| − | * [[RXN-7693]]
| + | |
| − | * [[RXN66-350]]
| + | |
| − | * [[3-ISOPROPYLMALDEHYDROG-RXN]]
| + | |
| − | * [[BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN]]
| + | |
| − | * [[1.1.1.145-RXN]]
| + | |
| − | * [[BADH-RXN]]
| + | |
| − | * [[CYSTINE-REDUCTASE-NADH-RXN]]
| + | |
| − | * [[RXN-16133]]
| + | |
| − | * [[GAPOXNPHOSPHN-RXN]]
| + | |
| − | * [[PGLYCDEHYDROG-RXN]]
| + | |
| − | * [[GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.]]
| + | |
| − | * [[BUTANAL-DEHYDROGENASE-RXN-BUTANAL/CO-A/NAD//BUTYRYL-COA/NADH/PROTON.42.]]
| + | |
| − | * [[1.3.1.9-RXN]]
| + | |
| − | * [[RXN0-276]]
| + | |
| − | * [[RXN0-2044]]
| + | |
| − | * [[2.4.2.31-RXN]]
| + | |
| − | * [[MYO-INOSITOL-2-DEHYDROGENASE-RXN]]
| + | |
| − | * [[RXN-14225]]
| + | |
| − | * [[RXN-14224]]
| + | |
| − | * [[RXN-13198]]
| + | |
| − | * [[RXN-16655]]
| + | |
| − | * [[RXN-16656]]
| + | |
| − | * [[ACETALD-DEHYDROG-RXN]]
| + | |
| − | * [[RXN-16653]]
| + | |
| | == External links == | | == External links == |
| − | * CAS : 53-84-9
| + | {{#set: direction=LEFT-TO-RIGHT}} |
| − | * METABOLIGHTS : MTBLC57540
| + | {{#set: ec number=EC-1.3.1.93}} |
| − | * PUBCHEM:
| + | {{#set: in pathway=PWY-7036}} |
| − | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=15938971 15938971]
| + | {{#set: reconstruction category=gap-filling}} |
| − | * HMDB : HMDB00902
| + | {{#set: reconstruction source=gap-filling-gapfilling_solution_with_meneco_draft_medium}} |
| − | * LIGAND-CPD:
| + | {{#set: reconstruction tool=meneco}} |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?C00003 C00003]
| + | {{#set: reconstruction comment=added for gapfilling}} |
| − | * CHEMSPIDER:
| + | |
| − | ** [http://www.chemspider.com/Chemical-Structure.10239196.html 10239196]
| + | |
| − | * CHEBI:
| + | |
| − | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57540 57540]
| + | |
| − | * BIGG : nad
| + | |
| − | {{#set: smiles=C1(C(=CC=C[N+]=1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O)}} | + | |
| − | {{#set: inchi key=InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-M}} | + | |
| − | {{#set: common name=NAD+}} | + | |
| − | {{#set: molecular weight=662.422 }} | + | |
| − | {{#set: common name=NAD+|beta-nicotinamide adenine dinucleotide|coenzyme I|diphosphopyridine nucleotide|diphosphopyridine nucleotide oxidized|nicotinamide adenine dinucleotide|nicotinamide adenine dinucleotide oxidized|NAD-oxidized|NAD-ox|DPN+|DPN-ox|DPN|β-nicotinamide adenine dinucleotide|NAD|β-NAD+}}
| + | |
| − | {{#set: consumed by=RXN-8001|RXN-4142|THREODEHYD-RXN|RXN-14249|RXN-12490|RXN66-479|RXN-17794|RXN-17777|RXN66-476-CPD-388/NAD/WATER//CPD-8462/NADH/PROTON.40.|RXN-17790|RXN66-476-CPD-14719/NAD/WATER//CPD-7830/NADH/PROTON.42.|RXN-12705|NADPYROPHOSPHAT-RXN|1.8.1.4-RXN|RXN66-3|RXN-17798|PREPHENATEDEHYDROG-RXN|RXN-905|RXN-10715|ISOCITRATE-DEHYDROGENASE-NAD+-RXN|RXN-9758|RXN-10912|RXN-10917|RXN-12507|PYRUVDEH-RXN|RXN-7682|RXN-17808|RXN-12750|2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|RXN66-472|PYRNUTRANSHYDROGEN-RXN|RXN6666-5|2OXOGLUTARATEDEH-RXN|RXN-37|RXN-7745|OHACYL-COA-DEHYDROG-RXN|NAD-KIN-RXN|RXN-3443|RXN66-342|RXN-1884|HISTALDEHYD-RXN|RXN-10698|RXN66-476|RXN-12693|RXN-17781|RXN-14271|RXN66-353|1.1.1.39-RXN|RXN-13158|UGD-RXN|ExchangeDeadEnd_NAD|RXN-10702|RXN-10703|RXN-10780|RXN-10089|RXN-12789|ALDHDEHYDROG-RXN|RXN0-1132|RXN-9336|RXN-17786|2-KETO-ADIPATE-DEHYDROG-RXN|3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|TransportSeed_NAD|PYRIDOXAL-4-DEHYDROGENASE-RXN|R222-RXN|1.2.1.25-RXN|RXN-13414|RXN66-478|RXN-11245}} | + | |
| − | {{#set: produced by=RXN-11195|TRANS-RXN0-277|RXN-16632|RXN-10062|RXN-5424|RXN-11478|1.5.1.20-RXN|RXN-3661|RXN3O-4113|DLACTDEHYDROGNAD-RXN|RXN1G-488|RXN1G-526|RXN-9659|RXN-9658|RXN-10911|TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10280/NAD//CPD-14282/NADH/PROTON.37.|RXN-11482|RXN-9635|ENOYL-ACP-REDUCT-NADH-RXN|RXN-10657|RXN-7694|1.1.1.8-RXN|GLYCERATE-DEHYDROGENASE-RXN|RXN-16628|RXN1F-152|RXN-16620|RXN-7700|RXN-16624|FERRIC-CHELATE-REDUCTASE-RXN|RXN-7706|1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.|TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10279/NAD//CPD-14281/NADH/PROTON.37.|RXN0-2145|RXN1G-395|BIOMASS-RXN|CYTOCHROME-B5-REDUCTASE-RXN|1.6.5.4-RXN|HOMOSERDEHYDROG-RXN-HOMO-SER/NAD//L-ASPARTATE-SEMIALDEHYDE/NADH/PROTON.51.|RXN-9662|RXN-9663|RXN-9660|RXN-9661|RXN-9558|RXN-12559|RXN-12558|RXN-12570|RXN-5822|RXN-9657|RXN-13417|RXN-10661|TransportSeed_NAD|ExchangeDeadEnd_NAD|NAD-SYNTH-GLN-RXN|RXN-10781|RXN-12568-HEXANAL/CO-A/NAD//HEXANOYL-COA/NADH/PROTON.43.}} | + | |
| − | {{#set: consumed or produced by=ExchangeSeed_NAD|NADH-DEHYDROG-A-RXN|RXN-7719|PHENDEHYD-RXN|RXN0-901|D-THREO-ALDOSE-1-DEHYDROGENASE-RXN|RXN-7644|RXN-7716|LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-348/NAD/WATER//PALMITATE/NADH/PROTON.41.|LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-7873/NAD/WATER//STEARIC_ACID/NADH/PROTON.45.|IMP-DEHYDROG-RXN|RXN-14280|GLYCOLATE-REDUCTASE-RXN|HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN|HEXADECANOL-DEHYDROGENASE-RXN|RXN-16654|NADH-DEHYDROGENASE-RXN|RXN-8629|RXN-12448|RXN-11662|RXN-12303-PLASTOQUINONE-9/NADH/PROTON//CPD-12829/NAD.43.|ALCOHOL-DEHYDROG-GENERIC-RXN|L-IDITOL-2-DEHYDROGENASE-RXN|RXN-10915|GLUTAMATE-DEHYDROGENASE-RXN|RETINOL-DEHYDROGENASE-RXN|HISTOLDEHYD-RXN|1.6.99.5-RXN-NADH/PLASTOQUINONE-9/PROTON//NAD/CPD-12829.43.|RXN-9510|MALATE-DEH-RXN|2KETO-3METHYLVALERATE-RXN|RXN-7657|ALCOHOL-DEHYDROG-RXN|RXN-161|RXN-1302|RXN-7693|RXN66-350|3-ISOPROPYLMALDEHYDROG-RXN|BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|1.1.1.145-RXN|BADH-RXN|CYSTINE-REDUCTASE-NADH-RXN|RXN-16133|GAPOXNPHOSPHN-RXN|PGLYCDEHYDROG-RXN|GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.|BUTANAL-DEHYDROGENASE-RXN-BUTANAL/CO-A/NAD//BUTYRYL-COA/NADH/PROTON.42.|1.3.1.9-RXN|RXN0-276|RXN0-2044|2.4.2.31-RXN|MYO-INOSITOL-2-DEHYDROGENASE-RXN|RXN-14225|RXN-14224|RXN-13198|RXN-16655|RXN-16656|ACETALD-DEHYDROG-RXN|RXN-16653}} | + | |
