Difference between revisions of "RXN-14957"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN] == * direction: **...")
 
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14957 RXN-14957] ==
 
* direction:
 
* direction:
−
** REVERSIBLE
+
** LEFT-TO-RIGHT
 +
* common name:
 +
** Lipoate synthase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.1.1.88 EC-1.1.1.88]
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** [http://enzyme.expasy.org/EC/2.8.1.8 EC-2.8.1.8]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[MEVALONATE]][c] '''+''' 1 [[CO-A]][c] '''+''' 2 [[NAD]][c] '''<=>''' 2 [[PROTON]][c] '''+''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 2 [[NADH]][c]
+
** 1 [[a-pyruvate-dehydrogenase-E2-protein-Nsup]][c] '''+''' 2 [[Reduced-2Fe-2S-Ferredoxins]][c] '''+''' 2 [[S-ADENOSYLMETHIONINE]][c] '''+''' 2 [[Sulfurated-Sulfur-Acceptors]][c] '''=>''' 2 [[Unsulfurated-Sulfur-Acceptors]][c] '''+''' 1 [[Pyruvate-dehydrogenase-lipoate]][c] '''+''' 2 [[CH33ADO]][c] '''+''' 2 [[Oxidized-2Fe-2S-Ferredoxins]][c] '''+''' 2 [[MET]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 (R)-mevalonate[c] '''+''' 1 coenzyme A[c] '''+''' 2 NAD+[c] '''<=>''' 2 H+[c] '''+''' 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''+''' 2 NADH[c]
+
** 1 a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine[c] '''+''' 2 a reduced [2Fe-2S] ferredoxin[c] '''+''' 2 S-adenosyl-L-methionine[c] '''+''' 2 a sulfurated [sulfur carrier][c] '''=>''' 2 an unsulfurated [sulfur carrier][c] '''+''' 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''+''' 2 5'-deoxyadenosine[c] '''+''' 2 an oxidized [2Fe-2S] ferredoxin[c] '''+''' 2 L-methionine[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[CHC_T00008509001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[CHC_T00008509001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5074]], mevalonate degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5074 PWY-5074]
+
* [[PWY-7382]], lipoate biosynthesis and incorporation (yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7382 PWY-7382]
−
** '''2''' reactions found over '''2''' reactions in the full pathway
+
** '''4''' reactions found over '''7''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[gap-filling]]:
+
* Category: [[orthology]]
−
** [[meneco]]:
+
** Source: [[orthology-galdieria.sulphuraria]]
−
*** [[added for gapfilling]]
+
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-original_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* RHEA:
+
{{#set: direction=LEFT-TO-RIGHT}}
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=14833 14833]
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{{#set: common name=Lipoate synthase}}
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* LIGAND-RXN:
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{{#set: ec number=EC-2.8.1.8}}
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** [http://www.genome.jp/dbget-bin/www_bget?R02081 R02081]
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{{#set: gene associated=CHC_T00008509001|CHC_T00008509001_1}}
−
* UNIPROT:
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{{#set: in pathway=PWY-7382}}
−
** [http://www.uniprot.org/uniprot/P09610 P09610]
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{{#set: reconstruction category=orthology|annotation}}
−
** [http://www.uniprot.org/uniprot/P12683 P12683]
+
{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome}}
−
** [http://www.uniprot.org/uniprot/P12684 P12684]
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
−
** [http://www.uniprot.org/uniprot/Q10283 Q10283]
+
−
{{#set: direction=REVERSIBLE}}
+
−
{{#set: ec number=EC-1.1.1.88}}
+
−
{{#set: in pathway=PWY-5074}}
+
−
{{#set: reconstruction category=gap-filling}}
+
−
{{#set: reconstruction tool=meneco}}
+
−
{{#set: reconstruction source=added for gapfilling}}
+

Latest revision as of 18:14, 9 January 2019

Reaction RXN-14957

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • Lipoate synthase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7382, lipoate biosynthesis and incorporation (yeast): PWY-7382
    • 4 reactions found over 7 reactions in the full pathway

Reconstruction information

External links

Retrieved from "http://gem-aureme.irisa.fr/ccrgem/index.php?title=RXN-14957&oldid=22847"