Difference between revisions of "2-ISOPROPYLMALATESYN-RXN"
From metabolic_network
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− | [[Category: | + | [[Category:Reaction]] |
− | == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=2-ISOPROPYLMALATESYN-RXN 2-ISOPROPYLMALATESYN-RXN] == |
+ | * direction: | ||
+ | ** LEFT-TO-RIGHT | ||
+ | * common name: | ||
+ | ** 2-isopropylmalate synthase | ||
+ | * ec number: | ||
+ | ** [http://enzyme.expasy.org/EC/2.3.3.13 EC-2.3.3.13] | ||
* Synonym(s): | * Synonym(s): | ||
− | == | + | == Reaction Formula == |
− | * [[ | + | * With identifiers: |
− | ** [[ | + | ** 1 [[WATER]][c] '''+''' 1 [[ACETYL-COA]][c] '''+''' 1 [[2-KETO-ISOVALERATE]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[3-CARBOXY-3-HYDROXY-ISOCAPROATE]][c] '''+''' 1 [[CO-A]][c] |
− | * [[ | + | * With common name(s): |
− | * | + | ** 1 H2O[c] '''+''' 1 acetyl-CoA[c] '''+''' 1 3-methyl-2-oxobutanoate[c] '''=>''' 1 H+[c] '''+''' 1 (2S)-2-isopropylmalate[c] '''+''' 1 coenzyme A[c] |
− | * [[ | + | |
− | ** [[ | + | == Genes associated with this reaction == |
− | == Pathways | + | Genes have been associated with this reaction based on different elements listed below. |
− | * [[ | + | * Gene: [[CHC_T00008989001_1]] |
− | * [[PWY- | + | ** Source: [[orthology-galdieria.sulphuraria]] |
+ | ** Source: [[orthology-ectocarpus_siliculosus]] | ||
+ | * Gene: [[CHC_T00009551001_1]] | ||
+ | ** Source: [[orthology-galdieria.sulphuraria]] | ||
+ | ** Source: [[orthology-ectocarpus_siliculosus]] | ||
+ | ** Source: [[orthology-arabidopsis_thaliana]] | ||
+ | * Gene: [[CHC_T00008989001]] | ||
+ | ** Source: [[annotation-original_genome]] | ||
+ | *** Assignment: AUTOMATED-NAME-MATCH | ||
+ | * Gene: [[CHC_T00009551001]] | ||
+ | ** Source: [[annotation-original_genome]] | ||
+ | *** Assignment: AUTOMATED-NAME-MATCH | ||
+ | == Pathways == | ||
+ | * [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY] | ||
+ | ** '''5''' reactions found over '''6''' reactions in the full pathway | ||
+ | * [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871] | ||
+ | ** '''6''' reactions found over '''7''' reactions in the full pathway | ||
+ | == Reconstruction information == | ||
+ | * Category: [[orthology]] | ||
+ | ** Source: [[orthology-galdieria.sulphuraria]] | ||
+ | *** Tool: [[pantograph]] | ||
+ | ** Source: [[orthology-arabidopsis_thaliana]] | ||
+ | *** Tool: [[pantograph]] | ||
+ | ** Source: [[orthology-ectocarpus_siliculosus]] | ||
+ | *** Tool: [[pantograph]] | ||
+ | * Category: [[annotation]] | ||
+ | ** Source: [[annotation-original_genome]] | ||
+ | *** Tool: [[pathwaytools]] | ||
== External links == | == External links == | ||
− | {{#set: | + | * RHEA: |
− | {{#set: pathway | + | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21524 21524] |
+ | * UNIPROT: | ||
+ | ** [http://www.uniprot.org/uniprot/P06208 P06208] | ||
+ | ** [http://www.uniprot.org/uniprot/Q58595 Q58595] | ||
+ | ** [http://www.uniprot.org/uniprot/P09151 P09151] | ||
+ | ** [http://www.uniprot.org/uniprot/Q9PLV9 Q9PLV9] | ||
+ | ** [http://www.uniprot.org/uniprot/Q9JUK6 Q9JUK6] | ||
+ | ** [http://www.uniprot.org/uniprot/Q58787 Q58787] | ||
+ | ** [http://www.uniprot.org/uniprot/P94565 P94565] | ||
+ | ** [http://www.uniprot.org/uniprot/Q9JP75 Q9JP75] | ||
+ | ** [http://www.uniprot.org/uniprot/Q02141 Q02141] | ||
+ | ** [http://www.uniprot.org/uniprot/P48575 P48575] | ||
+ | ** [http://www.uniprot.org/uniprot/O86511 O86511] | ||
+ | * LIGAND-RXN: | ||
+ | ** [http://www.genome.jp/dbget-bin/www_bget?R01213 R01213] | ||
+ | {{#set: direction=LEFT-TO-RIGHT}} | ||
+ | {{#set: common name=2-isopropylmalate synthase}} | ||
+ | {{#set: ec number=EC-2.3.3.13}} | ||
+ | {{#set: gene associated=CHC_T00008989001_1|CHC_T00009551001_1|CHC_T00008989001|CHC_T00009551001}} | ||
+ | {{#set: in pathway=LEUSYN-PWY|PWY-6871}} | ||
+ | {{#set: reconstruction category=orthology|annotation}} | ||
+ | {{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus}} | ||
+ | {{#set: reconstruction tool=pantograph|pathwaytools}} |
Latest revision as of 17:00, 9 January 2019
Contents
Reaction 2-ISOPROPYLMALATESYN-RXN
- direction:
- LEFT-TO-RIGHT
- common name:
- 2-isopropylmalate synthase
- ec number:
- Synonym(s):
Reaction Formula
- With identifiers:
- 1 WATER[c] + 1 ACETYL-COA[c] + 1 2-KETO-ISOVALERATE[c] => 1 PROTON[c] + 1 3-CARBOXY-3-HYDROXY-ISOCAPROATE[c] + 1 CO-A[c]
- With common name(s):
- 1 H2O[c] + 1 acetyl-CoA[c] + 1 3-methyl-2-oxobutanoate[c] => 1 H+[c] + 1 (2S)-2-isopropylmalate[c] + 1 coenzyme A[c]
Genes associated with this reaction
Genes have been associated with this reaction based on different elements listed below.
- Gene: CHC_T00008989001_1
- Source: orthology-galdieria.sulphuraria
- Source: orthology-ectocarpus_siliculosus
- Gene: CHC_T00009551001_1
- Source: orthology-galdieria.sulphuraria
- Source: orthology-ectocarpus_siliculosus
- Source: orthology-arabidopsis_thaliana
- Gene: CHC_T00008989001
- Source: annotation-original_genome
- Assignment: AUTOMATED-NAME-MATCH
- Source: annotation-original_genome
- Gene: CHC_T00009551001
- Source: annotation-original_genome
- Assignment: AUTOMATED-NAME-MATCH
- Source: annotation-original_genome
Pathways
- LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
- 5 reactions found over 6 reactions in the full pathway
- PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
- 6 reactions found over 7 reactions in the full pathway
Reconstruction information
- Category: orthology
- Source: orthology-galdieria.sulphuraria
- Tool: pantograph
- Source: orthology-arabidopsis_thaliana
- Tool: pantograph
- Source: orthology-ectocarpus_siliculosus
- Tool: pantograph
- Source: orthology-galdieria.sulphuraria
- Category: annotation
- Source: annotation-original_genome
- Tool: pathwaytools
- Source: annotation-original_genome
External links
- RHEA:
- UNIPROT:
- LIGAND-RXN: