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| − | [[Category:Reaction]] | + | [[Category:Metabolite]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHYLENETHFDEHYDROG-NADP-RXN METHYLENETHFDEHYDROG-NADP-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PROTEIN-LIPOYLLYSINE PROTEIN-LIPOYLLYSINE] == |
| − | * direction:
| + | |
| − | ** REVERSIBLE
| + | |
| | * common name: | | * common name: |
| − | ** Methylenetetrahydrofolate dehydrogenase | + | ** a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine |
| − | * ec number:
| + | |
| − | ** [http://enzyme.expasy.org/EC/1.5.1.5 EC-1.5.1.5]
| + | |
| | * Synonym(s): | | * Synonym(s): |
| | | | |
| − | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
| − | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
| − | ** 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[NADP]][c] '''<=>''' 1 [[5-10-METHENYL-THF-GLU-N]][c] '''+''' 1 [[NADPH]][c]
| + | * [[RXN-14950]] |
| − | * With common name(s):
| + | * [[RXN-13039]] |
| − | ** 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 NADP+[c] '''<=>''' 1 a 5,10-methenyltetrahydrofolate[c] '''+''' 1 NADPH[c]
| + | * [[RXN0-1141]] |
| − | | + | == Reaction(s) of unknown directionality == |
| − | == Genes associated with this reaction ==
| + | * [[RXN-8629]] |
| − | Genes have been associated with this reaction based on different elements listed below.
| + | * [[GCVP-RXN]] |
| − | * [[CHC_T00008670001_1]] | + | |
| − | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
| − | * [[CHC_T00008680001_1]] | + | |
| − | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
| − | * [[CHC_T00008680001]] | + | |
| − | ** ORIGINAL_GENOME
| + | |
| − | ***AUTOMATED-NAME-MATCH
| + | |
| − | == Pathways ==
| + | |
| − | * [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722]
| + | |
| − | ** '''3''' reactions found over '''3''' reactions in the full pathway
| + | |
| − | * [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
| + | |
| − | ** '''7''' reactions found over '''11''' reactions in the full pathway
| + | |
| − | * [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
| + | |
| − | ** '''6''' reactions found over '''9''' reactions in the full pathway
| + | |
| − | * [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY]
| + | |
| − | ** '''4''' reactions found over '''9''' reactions in the full pathway
| + | |
| − | * [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497] | + | |
| − | ** '''7''' reactions found over '''24''' reactions in the full pathway
| + | |
| − | * [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201] | + | |
| − | ** '''5''' reactions found over '''12''' reactions in the full pathway
| + | |
| − | == Reconstruction information ==
| + | |
| − | * [[orthology]]:
| + | |
| − | ** [[pantograph]]:
| + | |
| − | *** [[galdieria.sulphuraria]]
| + | |
| − | * [[annotation]]:
| + | |
| − | ** [[pathwaytools]]:
| + | |
| − | *** [[original_genome]]
| + | |
| | == External links == | | == External links == |
| − | * RHEA:
| + | {{#set: common name=a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine}} |
| − | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22812 22812]
| + | {{#set: produced by=RXN-14950|RXN-13039|RXN0-1141}} |
| − | * LIGAND-RXN:
| + | {{#set: reversible reaction associated=RXN-8629|GCVP-RXN}} |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?R01220 R01220]
| + | |
| − | * UNIPROT:
| + | |
| − | ** [http://www.uniprot.org/uniprot/P09440 P09440]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P07245 P07245]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P11586 P11586]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P44313 P44313]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P47259 P47259]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P54382 P54382]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O67736 O67736]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9JWI9 Q9JWI9]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9PP68 Q9PP68]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P24186 P24186]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q60006 Q60006]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q27772 Q27772]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P51696 P51696]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O65269 O65269]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O65271 O65271]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O68031 O68031]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9ZTV0 Q9ZTV0]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9X7F6 Q9X7F6]
| + | |
| − | {{#set: direction=REVERSIBLE}}
| + | |
| − | {{#set: common name=Methylenetetrahydrofolate dehydrogenase}} | + | |
| − | {{#set: ec number=EC-1.5.1.5}} | + | |
| − | {{#set: gene associated=CHC_T00008670001_1|CHC_T00008680001_1|CHC_T00008680001}}
| + | |
| − | {{#set: in pathway=PWY-1722|PWY-3841|1CMET2-PWY|CODH-PWY|PWY-5497|PWY-2201}} | + | |
| − | {{#set: reconstruction category=orthology}}
| + | |
| − | {{#set: reconstruction tool=pantograph}}
| + | |
| − | {{#set: reconstruction source=galdieria.sulphuraria}}
| + | |
| − | {{#set: reconstruction category=annotation}}
| + | |
| − | {{#set: reconstruction tool=pathwaytools}}
| + | |
| − | {{#set: reconstruction source=original_genome}}
| + | |
