PROTOHEMEFERROCHELAT-RXN

Reaction PROTOHEMEFERROCHELAT-RXN

• direction:
  • REVERSIBLE
• common name:
  • ferrochelatase
• ec number:
  • EC-4.99.1.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 PROTON[c] + 1 PROTOHEME[c] <=> 1 PROTOPORPHYRIN_IX[c] + 1 FE+2[c]
• With common name(s):
  • 2 H+[c] + 1 ferroheme b[c] <=> 1 protoporphyrin IX[c] + 1 Fe2+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00008918001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
• Gene: CHC_T00008918001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• PWY0-1415, superpathway of heme biosynthesis from uroporphyrinogen-III: PWY0-1415
  • 5 reactions found over 6 reactions in the full pathway
• HEMESYN2-PWY, heme biosynthesis II (anaerobic): HEMESYN2-PWY
  • 2 reactions found over 4 reactions in the full pathway
• HEME-BIOSYNTHESIS-II, heme biosynthesis I (aerobic): HEME-BIOSYNTHESIS-II
  • 4 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 22584
• UNIPROT:
  • P22830
  • P22315
  • P28602
  • Q05338
  • P42043
  • P23871
  • P32396
  • Q9CFB4
  • P56107
  • O67083
  • Q9PI08
  • Q9JVA5
  • P22600
  • P43868
  • P16622
  • Q59735
  • P43413
  • P54225
  • P42045
  • O64391
  • P42044
• LIGAND-RXN:
  • R00310