Difference between revisions of "THYMIDYLATESYN-RXN"

Latest revision as of 10:38, 27 June 2019

Reaction THYMIDYLATESYN-RXN

• ec number:
  • EC-2.1.1.45
• direction:
  • LEFT-TO-RIGHT
• common name:
  • thymidylate synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 METHYLENE-THF-GLU-N[c] + 1 DUMP[c] => 1 TMP[c] + 1 DIHYDROFOLATE-GLU-N[c]
• With common name(s):
  • 1 a 5,10-methylene-tetrahydrofolate[c] + 1 dUMP[c] => 1 dTMP[c] + 1 a 7,8-dihydrofolate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g14068.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• PWY-7198, pyrimidine deoxyribonucleotides de novo biosynthesis IV: PWY-7198
  • 6 reactions found over 7 reactions in the full pathway
• PWY0-166, superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli): PWY0-166
  • 14 reactions found over 17 reactions in the full pathway
• PWY-7187, pyrimidine deoxyribonucleotides de novo biosynthesis II: PWY-7187
  • 6 reactions found over 7 reactions in the full pathway
• 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
  • 8 reactions found over 9 reactions in the full pathway
• PWY-3841, folate transformations II: PWY-3841
  • 9 reactions found over 11 reactions in the full pathway
• PWY-7184, pyrimidine deoxyribonucleotides de novo biosynthesis I: PWY-7184
  • 9 reactions found over 9 reactions in the full pathway
• PWY-7210, pyrimidine deoxyribonucleotides biosynthesis from CTP: PWY-7210
  • 7 reactions found over 8 reactions in the full pathway
• PWY-7199, pyrimidine deoxyribonucleosides salvage: PWY-7199
  • 2 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• UNIPROT:
  • P19368
  • Q07422
  • P47469
  • Q9JT57
  • P42326
  • O02604
  • P07382
  • P16126
  • P13922
  • P20712
  • P11044
  • P45350
  • P45352
  • P51820
  • P0C0M4
  • Q27828
  • P09249
  • P12462
  • P07606
  • P00471
  • P0A884
  • P00469
  • O81395
  • Q05763
  • Q39687
  • Q9YTJ6
  • P06785
  • P04818
  • P07607
  • P13100
• RHEA:
  • 12105
• LIGAND-RXN:
  • R02101