PROTOHEMEFERROCHELAT-RXN

Reaction PROTOHEMEFERROCHELAT-RXN

• ec number:
  • EC-4.99.1.1
• direction:
  • REVERSIBLE
• common name:
  • ferrochelatase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTOHEME[c] + 2 PROTON[c] <=> 1 PROTOPORPHYRIN_IX[c] + 1 FE+2[c]
• With common name(s):
  • 1 ferroheme b[c] + 2 H+[c] <=> 1 protoporphyrin IX[c] + 1 Fe2+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g13940.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g17044.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica

Pathways

• HEMESYN2-PWY, heme b biosynthesis II (anaerobic): HEMESYN2-PWY
  • 3 reactions found over 4 reactions in the full pathway
• HEME-BIOSYNTHESIS-II, heme b biosynthesis I (aerobic): HEME-BIOSYNTHESIS-II
  • 4 reactions found over 4 reactions in the full pathway
• PWY0-1415, superpathway of heme b biosynthesis from uroporphyrinogen-III: PWY0-1415
  • 5 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P22830
  • P22315
  • P28602
  • Q05338
  • P42043
  • P23871
  • P32396
  • Q9CFB4
  • P56107
  • O67083
  • Q9PI08
  • Q9JVA5
  • P22600
  • P43868
  • P16622
  • Q59735
  • P43413
  • P54225
  • P42045
  • O64391
  • P42044
• RHEA:
  • 22584
• LIGAND-RXN:
  • R00310