RXN0-2023

Reaction RXN0-2023

• ec number:
  • EC-2.8.1.13
• direction:
  • LEFT-TO-RIGHT
• common name:
  • tRNA-specific 2-thiouridylase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 tRNA-uridine34[c] + 1 TusE-S-sulfanylcysteine[c] + 1 ATP[c] + 1 Donor-H2[c] => 1 tRNA-2-thiouridine34[c] + 1 TusE-L-cysteine[c] + 1 AMP[c] + 1 PPI[c] + 1 Acceptor[c] + 1 PROTON[c]
• With common name(s):
  • 1 a uridine34 in tRNA[c] + 1 a [TusE sulfur carrier protein]-S-sulfanylcysteine[c] + 1 ATP[c] + 1 a reduced electron acceptor[c] => 1 a 2-thiouridine34 in tRNA[c] + 1 a [TusE sulfur carrier protein]-L-cysteine[c] + 1 AMP[c] + 1 diphosphate[c] + 1 an oxidized electron acceptor[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g17558.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g8010.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Pathways

• PWY-7892, tRNA-uridine 2-thiolation (bacteria): PWY-7892
  • 3 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools