RXN3O-130

Reaction RXN3O-130

• ec number:
  • EC-1.14.13.70
• direction:
  • LEFT-TO-RIGHT
• common name:
  • sterol 14-demethylase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 LANOSTEROL[c] + 3 OXYGEN-MOLECULE[c] + 3 NADPH[c] + 2 PROTON[c] => 1 44-DIMETHYL-CHOLESTA-814-24-TRIENOL[c] + 1 FORMATE[c] + 3 NADP[c] + 4 WATER[c]
• With common name(s):
  • 1 lanosterol[c] + 3 oxygen[c] + 3 NADPH[c] + 2 H+[c] => 1 4,4-dimethyl-cholesta-8,14,24-trienol[c] + 1 formate[c] + 3 NADP+[c] + 4 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g18563.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g4142.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g12685.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g11283.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g12686.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g12684.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g12687.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g4115.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g14468.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g14467.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g13113.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM

Pathways

• PWY-6074, zymosterol biosynthesis: PWY-6074
  • 6 reactions found over 12 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 25287
• LIGAND-RXN:
  • R05640