1-PHOSPHATIDYLINOSITOL-KINASE-RXN

Reaction 1-PHOSPHATIDYLINOSITOL-KINASE-RXN

• ec number:
  • EC-2.7.1.67
• direction:
  • LEFT-TO-RIGHT
• common name:
  • phosphatidylinositol 4-kinase
  • 1-phosphatidylinositol 4-kinase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 L-1-phosphatidyl-inositols[c] + 1 ATP[c] => 1 CPD-1108[c] + 1 ADP[c] + 1 PROTON[c]
• With common name(s):
  • 1 a 1-phosphatidyl-1D-myo-inositol[c] + 1 ATP[c] => 1 a 1-phosphatidyl-1D-myo-inositol 4-phosphate[c] + 1 ADP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g4227.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12356.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g14400.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g13869.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g7362.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g7362.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g3661.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g4225.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g3660.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-6352, 3-phosphoinositide biosynthesis: PWY-6352
  • 6 reactions found over 8 reactions in the full pathway
• PWY-6351, D-myo-inositol (1,4,5)-trisphosphate biosynthesis: PWY-6351
  • 4 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• UNIPROT:
  • P18688
  • P12798
  • P39104
  • P42356
  • Q9UBF8
  • P37297
  • Q28925
  • O81281
  • O81129
  • Q9ZPE1
• RHEA:
  • 19878
• LIGAND-RXN:
  • R03361