2.4.1.68-RXN

Reaction 2.4.1.68-RXN

• ec number:
  • EC-2.4.1.68
• direction:
  • LEFT-TO-RIGHT
• common name:
  • glycoprotein 6-alpha-L-fucosyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-13118[c] + 1 2-2-N-linked-Glycan[c] => 1 N4-N-ACETYL-BETA-D-GLUCOSAMINYL-F6[c] + 1 GDP[c] + 1 PROTON[c]
• With common name(s):
  • 1 GDP-β-L-fucose[c] + 1 Man3GlcNAc4-[protein][c] => 1 an N4-{β-D-GlcNAc-(1→2)-α-D-Man-(1→3)-[β-D-GlcNAc-(1→2)-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-[α-L-Fuc-(1→6)]-β-D-GlcNAc}-L-asparaginyl-[protein][c] + 1 GDP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g10466.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g18151.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g18151.t1
  • Source: orthology-saccharina_japonica
• Gene: g5415.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g10466.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g3761.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g5426.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g5416.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM

Pathways

• PWY-7426, complex N-linked glycan biosynthesis (vertebrates): PWY-7426
  • 4 reactions found over 10 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • Q9BYC5
• RHEA:
  • 12985
• LIGAND-RXN:
  • R05988