RXN-12461

Reaction RXN-12461

• ec number:
  • EC-2.1.1.229
• direction:
  • LEFT-TO-RIGHT
• common name:
  • tRNA (carboxymethyluridine34-5-O)-methyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 S-ADENOSYLMETHIONINE[c] + 1 carbo-me-ur-34-tRNA[c] => 1 5-2-me-oxy-2-oxo-et-ur-34-tRNA[c] + 1 ADENOSYL-HOMO-CYS[c]
• With common name(s):
  • 1 S-adenosyl-L-methionine[c] + 1 a carboxymethyluridine34 in tRNA[c] => 1 a 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA[c] + 1 S-adenosyl-L-homocysteine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g18386.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g18386.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g4374.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Pathways

• PWY-7888, tRNA-uridine 2-thiolation (cytoplasmic): PWY-7888
  • 2 reactions found over 7 reactions in the full pathway
• PWY-6829, tRNA methylation (yeast): PWY-6829
  • 14 reactions found over 15 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 43209