RXN-12508

Reaction RXN-12508

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 2-(α-hydroxyethyl)-TPP:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine acetyltransferase
  • pyruvate dehydrogenase (NAD+)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 2-ALPHA-HYDROXYETHYL-THPP[c] + 1 Pyruvate-dehydrogenase-lipoate[c] => 1 Pyruvate-dehydrogenase-acetylDHlipoyl[c] + 1 THIAMINE-PYROPHOSPHATE[c]
• With common name(s):
  • 1 2-(α-hydroxyethyl)thiamine diphosphate[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] => 1 a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine[c] + 1 thiamine diphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g11188.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g16637.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g6561.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g6722.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g14052.t1
  • Source: orthology-saccharina_japonica

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• LIGAND-RXN:
  • R03270

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