RXN-15561

Reaction RXN-15561

• ec number:
  • EC-2.3.2.27
• direction:
  • LEFT-TO-RIGHT
• common name:
  • RING-type E3 ubiquitin transferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 S-ubiquitinyl-UCP-E2-L-cysteine[c] + 1 Protein-L-lysine[c] => 1 PROTEIN-N-UBIQUITYL-LYSINE[c] + 1 PROTON[c] + 1 Ubiquitin-carrier-protein-E2-L-cysteine[c]
• With common name(s):
  • 1 an [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine[c] + 1 a [protein]-L-lysine[c] => 1 a [protein]-N6-monoubiquitinyl-L-lysine[c] + 1 H+[c] + 1 an [E2 ubiquitin-conjugating enzyme]-L-cysteine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g14973.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g5761.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g7706.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g18336.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g11070.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g6797.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g4966.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g4415.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g7587.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g3903.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g16057.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g6242.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g13002.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g9969.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g16055.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g4150.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g7381.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g11773.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g11203.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g6830.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g6593.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g3445.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g10395.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12881.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g4118.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g6797.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g18030.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g16080.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g4118.t3
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12664.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g17042.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8043.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g9159.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g3555.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g17042.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8780.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g11006.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g14659.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g12320.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g9378.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g8708.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g13002.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g4965.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g4538.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8043.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g6242.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g3901.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g7706.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g8780.t3
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g17557.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g9909.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g4538.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g18143.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g3445.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8151.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g8028.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g4118.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12602.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g9431.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g7016.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8780.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12881.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g9430.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g12596.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g11708.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12682.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g18144.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g10583.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12516.t1
  • Source: orthology-saccharina_japonica
• Gene: g10408.t1
  • Source: orthology-saccharina_japonica
• Gene: g15511.t1
  • Source: orthology-saccharina_japonica
• Gene: g11857.t1
  • Source: orthology-saccharina_japonica
• Gene: g8043.t3
  • Source: orthology-saccharina_japonica
• Gene: g9336.t1
  • Source: orthology-saccharina_japonica
• Gene: g10408.t2
  • Source: orthology-saccharina_japonica
• Gene: g11762.t1
  • Source: orthology-saccharina_japonica
• Gene: g6560.t1
  • Source: orthology-saccharina_japonica
• Gene: g7651.t1
  • Source: orthology-saccharina_japonica
• Gene: g8131.t1
  • Source: orthology-saccharina_japonica
• Gene: g9336.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g8824.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g5858.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g6581.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER

Pathways

• PWY-7511, protein ubiquitination: PWY-7511
  • 7 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph