3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN

Reaction 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN

• ec number:
  • EC-1.1.1.31
• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-hydroxyisobutyrate dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 CPD-12175[c] => 1 PROTON[c] + 1 NADH[c] + 1 CH3-MALONATE-S-ALD[c]
• With common name(s):
  • 1 NAD+[c] + 1 (S)-3-hydroxy-isobutanoate[c] => 1 H+[c] + 1 NADH[c] + 1 (S)-methylmalonate-semialdehyde[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g3371.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g17305.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g3370.t1
  • Source: orthology-arabidopsis_thaliana
• Gene: g12553.t1
  • Source: orthology-saccharina_japonica
• Gene: g3527.t1
  • Source: orthology-ectocarpus_siliculosus
• Gene: g10495.t1
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g14423.t1
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g10495.t2
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica

Pathways

• VALDEG-PWY, L-valine degradation I: VALDEG-PWY
  • 6 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P29266
  • P28811
  • Q8XAE4
  • Q55702
  • Q9XTI0
• RHEA:
  • 17682
• LIGAND-RXN:
  • R02047