RXN-10608

Reaction RXN-10608

• ec number:
  • EC-2.4.1.17
• direction:
  • LEFT-TO-RIGHT
• common name:
  • glucuronosyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 UDP-GLUCURONATE[c] + 1 L-THYROXINE[c] => 1 CPD-11401[c] + 1 UDP[c] + 1 PROTON[c]
• With common name(s):
  • 1 UDP-α-D-glucuronate[c] + 1 L-thyroxine[c] => 1 L-thyroxine acyl β-D-glucuronide[c] + 1 UDP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g3454.t2
  • Source: orthology-saccharina_japonica
• Gene: g12692.t1
  • Source: orthology-saccharina_japonica
• Gene: g8915.t1
  • Source: orthology-saccharina_japonica
• Gene: g8051.t1
  • Source: orthology-saccharina_japonica
• Gene: g8053.t1
  • Source: orthology-saccharina_japonica
• Gene: g8052.t1
  • Source: orthology-saccharina_japonica
• Gene: g8915.t2
  • Source: orthology-saccharina_japonica
• Gene: g3454.t1
  • Source: orthology-saccharina_japonica
• Gene: g14258.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g5428.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g13335.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g7975.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g13335.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g4449.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g14997.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g9602.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g18599.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g3760.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g13334.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g5881.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g15675.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g13333.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g18599.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g16124.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g6079.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10340.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g16308.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g14021.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10341.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g11483.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g10339.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM

Pathways

• PWY-6261, thyroid hormone metabolism II (via conjugation and/or degradation): PWY-6261
  • 11 reactions found over 15 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools