CORTISONE-ALPHA-REDUCTASE-RXN

Reaction CORTISONE-ALPHA-REDUCTASE-RXN

• ec number:
  • EC-1.3.1.22
• direction:
  • LEFT-TO-RIGHT
• common name:
  • cortisone α-reductase
  • cortisone 5α-reductase
• Synonym(s):
  • cortisone Δ4-5α-reductase
  • microsomal steroid reductase (5α)
  • Δ4-3-ketosteroid reductase (5α)
  • Δ4-3-oxosteroid-5α-reductase
  • NADPH:Δ4-3-oxosteroid-5α-oxidoreductase
  • Δ4-5α-reductase

Reaction Formula

• With identifiers:
  • 1 NADPH[c] + 1 CORTISONE[c] + 1 PROTON[c] => 1 CPD-286[c] + 1 NADP[c]
• With common name(s):
  • 1 NADPH[c] + 1 cortisone[c] + 1 H+[c] => 1 4,5α-dihydrocortisone[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g4721.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g12550.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g9244.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g9245.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 17981
• LIGAND-RXN:
  • R02892