RXN-12570

Reaction RXN-12570

• ec number:
  • EC-1.1.1.35
• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-hydroxyhexanoyl-CoA dehydrogenase
  • 3-hydroxyacyl-CoA dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 1 K-HEXANOYL-COA[c] + 1 NADH[c] => 1 OH-HEXANOYL-COA[c] + 1 NAD[c]
• With common name(s):
  • 1 H+[c] + 1 3-oxohexanoyl-CoA[c] + 1 NADH[c] => 1 (S)-3-hydroxyhexanoyl-CoA[c] + 1 NAD+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g10495.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g12553.t1
  • Source: orthology-saccharina_japonica
• Gene: g10833.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g3370.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-arabidopsis_thaliana
• Gene: g17267.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g3527.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g14423.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica
• Gene: g7899.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-saccharina_japonica
• Gene: g10495.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g3371.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• PWY-6863, pyruvate fermentation to hexanol (engineered): PWY-6863
  • 8 reactions found over 11 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 31144
• LIGAND-RXN:
  • R04748