RXN-11056

Reaction RXN-11056

• ec number:
  • EC-1.14.14.1
• direction:
  • LEFT-TO-RIGHT
• common name:
  • melatonin 6-hydroxylase
  • aromatase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 N-ACETYL-5-METHOXY-TRYPTAMINE[c] + 1 Red-NADPH-Hemoprotein-Reductases[c] + 1 OXYGEN-MOLECULE[c] => 1 CPD-12014[c] + 1 Ox-NADPH-Hemoprotein-Reductases[c] + 1 WATER[c]
• With common name(s):
  • 1 melatonin[c] + 1 a reduced [NADPH-hemoprotein reductase][c] + 1 oxygen[c] => 1 6-hydroxymelatonin[c] + 1 an oxidized [NADPH-hemoprotein reductase][c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g14450.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g5981.t1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g11939.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g12821.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g5376.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g11939.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
• Gene: g6801.t1
  • Source: orthology-saccharina_japonica

Pathways

• PWY-6398, melatonin degradation I: PWY-6398
  • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools