GLUTCYSLIG-RXN

Reaction GLUTCYSLIG-RXN

• ec number:
  • EC-6.3.2.2
• direction:
  • LEFT-TO-RIGHT
• common name:
  • glutamate-cysteine ligase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GLT[c] + 1 CYS[c] + 1 ATP[c] => 1 PROTON[c] + 1 L-GAMMA-GLUTAMYLCYSTEINE[c] + 1 Pi[c] + 1 ADP[c]
• With common name(s):
  • 1 L-glutamate[c] + 1 L-cysteine[c] + 1 ATP[c] => 1 H+[c] + 1 γ-L-glutamyl-L-cysteine[c] + 1 phosphate[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g16438.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g11493.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
• Gene: g12069.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-saccharina_japonica
• Gene: g13176.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina

Pathways

• PWY-6840, homoglutathione biosynthesis: PWY-6840
  • 1 reactions found over 2 reactions in the full pathway
• PWY-7255, ergothioneine biosynthesis I (bacteria): PWY-7255
  • 2 reactions found over 7 reactions in the full pathway
• GLUTATHIONESYN-PWY, glutathione biosynthesis: GLUTATHIONESYN-PWY
  • 2 reactions found over 2 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P19468
  • Q56277
  • Q9JZI4
  • Q9JU83
  • P48507
  • P48506
  • P32477
  • P0A6W9
  • O22493
  • P46309
  • Q9TY17
  • Q09768
• RHEA:
  • 13286
• LIGAND-RXN:
  • R00894