RXN-11213

Reaction RXN-11213

• ec number:
  • EC-1.2.1.27
• direction:
  • LEFT-TO-RIGHT
• common name:
  • methylmalonate-semialdehyde dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CH3-MALONATE-S-ALD[c] + 1 CO-A[c] + 1 NAD[c] + 1 WATER[c] => 1 PROPIONYL-COA[c] + 1 HCO3[c] + 1 NADH[c] + 1 PROTON[c]
• With common name(s):
  • 1 (S)-methylmalonate-semialdehyde[c] + 1 coenzyme A[c] + 1 NAD+[c] + 1 H2O[c] => 1 propanoyl-CoA[c] + 1 hydrogencarbonate[c] + 1 NADH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g8161.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g13104.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica

Pathways

• VALDEG-PWY, L-valine degradation I: VALDEG-PWY
  • 6 reactions found over 8 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• RHEA:
  • 20805
• LIGAND-RXN:
  • R00935