RXN-11373

Reaction RXN-11373

• direction:
  • LEFT-TO-RIGHT
• common name:
  • diphthamide synthase
  • diphthine synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 S-ADENOSYLMETHIONINE[c] + 1 3-carboxy-3-dimethylammonio-propyl-L-his[c] => 1 DIPHTINE[c] + 1 ADENOSYL-HOMO-CYS[c] + 1 PROTON[c]
• With common name(s):
  • 1 S-adenosyl-L-methionine[c] + 1 a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2][c] => 1 a diphthine-[translation elongation factor 2][c] + 1 S-adenosyl-L-homocysteine[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g15487.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
• Gene: g8266.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-saccharina_japonica
• Gene: g15487.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM

Reconstruction information

• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools
• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph

External links

• RHEA:
  • 36428
• LIGAND-RXN:
  • R08469