THI-P-SYN-RXN

Reaction THI-P-SYN-RXN

• ec number:
  • EC-2.5.1.3
• direction:
  • LEFT-TO-RIGHT
• common name:
  • thiamine phosphate synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 THZ-P[c] + 1 PROTON[c] + 1 AMINO-HYDROXYMETHYL-METHYLPYRIMIDINE-PP[c] => 1 PPI[c] + 1 THIAMINE-P[c]
• With common name(s):
  • 1 4-methyl-5-(2-phosphooxyethyl)thiazole[c] + 1 H+[c] + 1 4-amino-2-methyl-5-(diphosphomethyl)pyrimidine[c] => 1 diphosphate[c] + 1 thiamine phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g14017.t1
  • Source: orthology-ectocarpus_siliculosus
• Gene: g14705.t2
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica
• Gene: g14705.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: EC-NUMBER
  • Source: orthology-saccharina_japonica

Pathways

• PWY-7356, thiamine salvage IV (yeast): PWY-7356
  • 4 reactions found over 7 reactions in the full pathway
• PWY-6908, thiamine diphosphate biosynthesis IV (eukaryotes): PWY-6908
  • 2 reactions found over 3 reactions in the full pathway
• PWY-7357, thiamine formation from pyrithiamine and oxythiamine (yeast): PWY-7357
  • 2 reactions found over 6 reactions in the full pathway
• PWY-6897, thiamine salvage II: PWY-6897
  • 2 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P41835
  • P71350
  • O25514
  • Q9PNL3
  • Q9JWI2
  • Q9ZL01
  • P30137
  • P39594
  • P40386
  • P72965
  • O48881
  • O34294
  • Q9ZBL5
• RHEA:
  • 22329
• LIGAND-RXN:
  • R03223