CPD-14594

Reaction RXN0-901

• direction:
  • REVERSIBLE
• common name:
  • xanthine dehydrogenase
• ec number:
  • EC-1.17.1.4
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 XANTHINE[c] + 1 WATER[c] + 1 NAD[c] <=> 1 NADH[c] + 1 PROTON[c] + 1 URATE[c]
• With common name(s):
  • 1 xanthine[c] + 1 H2O[c] + 1 NAD+[c] <=> 1 NADH[c] + 1 H+[c] + 1 urate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-20_000230
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-aragem
• Gene: Ec-20_000210
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-aragem

Pathways

• PWY-5497, purine nucleobases degradation II (anaerobic): PWY-5497
  • 8 reactions found over 24 reactions in the full pathway
• SALVADEHYPOX-PWY, adenosine nucleotides degradation II: SALVADEHYPOX-PWY
  • 5 reactions found over 5 reactions in the full pathway
• P164-PWY, purine nucleobases degradation I (anaerobic): P164-PWY
  • 4 reactions found over 17 reactions in the full pathway
• PWY-6596, adenosine nucleotides degradation I: PWY-6596
  • 6 reactions found over 8 reactions in the full pathway
• PWY-6607, guanosine nucleotides degradation I: PWY-6607
  • 2 reactions found over 4 reactions in the full pathway
• PWY-6606, guanosine nucleotides degradation II: PWY-6606
  • 3 reactions found over 4 reactions in the full pathway
• PWY-6999, theophylline degradation: PWY-6999
  • 2 reactions found over 9 reactions in the full pathway
• PWY-6608, guanosine nucleotides degradation III: PWY-6608
  • 2 reactions found over 4 reactions in the full pathway
• PWY-5695, urate biosynthesis/inosine 5'-phosphate degradation: PWY-5695
  • 3 reactions found over 4 reactions in the full pathway
• PWY-6538, caffeine degradation III (bacteria, via demethylation): PWY-6538
  • 2 reactions found over 7 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 16669
• LIGAND-RXN:
  • R02103
• UNIPROT:
  • Q62637
  • P22811
  • Q12553
  • P08793
  • P10351
  • Q7M0I7
  • Q7M0I8
  • Q7M0I9
  • P47990
  • P47989
  • Q00519