RNDR2

Reaction MOHMT

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-methyl-2-oxobutanoate hydroxymethyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 mlthf[c] + 1.0 3mob[c] + 1.0 h2o[c] => 1.0 thf[c] + 1.0 2dhp[c]
• With common name(s):
  • 1.0 5,10-Methylenetetrahydrofolate[c] + 1.0 3-Methyl-2-oxobutanoate[c] + 1.0 H2O H2O[c] => 1.0 5,6,7,8-Tetrahydrofolate[c] + 1.0 2-Dehydropantoate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF1860
  • pantograph-e_coli_sstr_k12_substr_mg1655
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map01100: map01100
  • 460 reactions found over 2349 reactions in the full pathway
• map01110: map01110
  • 179 reactions found over 1054 reactions in the full pathway
• map00770: map00770
  • 17 reactions found over 75 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-e_coli_sstr_k12_substr_mg1655
    • Tool: pantograph
  • Source: orthology-b_subtilis_subsp_subtilis_str168
    • Tool: pantograph

External links

• RHEA:
  • 11824
• MetaNetX (MNX) Equation : MNXR101702
• KEGG Reaction : R01226
• EC Number : 2.1.2.11