M1PD

Reaction TMDS

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Thymidylate synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 dump[c] + 1.0 mlthf[c] => 1.0 dtmp[c] + 1.0 dhf[c]
• With common name(s):
  • 1.0 DUMP C9H11N2O8P[c] + 1.0 5,10-Methylenetetrahydrofolate[c] => 1.0 DTMP C10H13N2O8P[c] + 1.0 7,8-Dihydrofolate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF1576
  • pantograph-l_plantarum_wcfs1
  • pantograph-e_coli_sstr_k12_substr_mg1655
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map01100: map01100
  • 508 reactions found over 2349 reactions in the full pathway
• map00240: map00240
  • 83 reactions found over 244 reactions in the full pathway
• map00670: map00670
  • 14 reactions found over 65 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • e_coli_sstr_k12_substr_mg1655
    • l_plantarum_wcfs1
    • b_subtilis_subsp_subtilis_str168

External links

• RHEA:
  • 12104
• MetaNetX (MNX) Equation : MNXR104889
• KEGG Reaction : R02101
• EC Number : 2.1.1.45