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Reaction GTPCI

• direction:
  • LEFT-TO-RIGHT
• common name:
  • GTP cyclohydrolase I
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 gtp[c] + 1.0 h2o[c] => 1.0 ahdt[c] + 1.0 for[c] + 1.0 h[c]
• With common name(s):
  • 1.0 GTP C10H12N5O14P3[c] + 1.0 H2O H2O[c] => 1.0 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate[c] + 1.0 Formate[c] + 1.0 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF3267
  • pantograph-l_plantarum_wcfs1
  • pantograph-e_coli_sstr_k12_substr_mg1655
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map01100: map01100
  • 460 reactions found over 2349 reactions in the full pathway
• map00790: map00790
  • 12 reactions found over 41 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • e_coli_sstr_k12_substr_mg1655
    • l_plantarum_wcfs1
    • b_subtilis_subsp_subtilis_str168

External links

• EC Number : 3.5.4.16
• BioCyc : META:GTP-CYCLOHYDRO-I-RXN
• MetaNetX (MNX) Equation : MNXR100453
• RHEA:
  • 17473
• Reactome : REACT_R-ATH-1474146
• KEGG Reaction : R00424