EF1565

Reaction DHFS

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Dihydrofolate synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 glu__L[c] + 1.0 atp[c] + 1.0 dhpt[c] => 1.0 h[c] + 1.0 dhf[c] + 1.0 adp[c] + 1.0 pi[c]
• With common name(s):
  • 1.0 L-Glutamate[c] + 1.0 ATP C10H12N5O13P3[c] + 1.0 Dihydropteroate[c] => 1.0 H+[c] + 1.0 7,8-Dihydrofolate[c] + 1.0 ADP C10H12N5O10P2[c] + 1.0 Phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF2928
  • pantograph-l_plantarum_wcfs1
  • pantograph-e_coli_sstr_k12_substr_mg1655
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map01100: map01100
  • 508 reactions found over 2349 reactions in the full pathway
• map00790: map00790
  • 12 reactions found over 41 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • e_coli_sstr_k12_substr_mg1655
    • l_plantarum_wcfs1
    • b_subtilis_subsp_subtilis_str168

External links

• RHEA:
  • 23584
• BioCyc : META:DIHYDROFOLATESYNTH-RXN
• MetaNetX (MNX) Equation : MNXR97403
• KEGG Reaction : R02237
• EC Number : 6.3.2.12