APATi

Reaction PDH

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Pyruvate dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 pyr[c] + 1.0 nad[c] + 1.0 coa[c] => 1.0 nadh[c] + 1.0 co2[c] + 1.0 accoa[c]
• With common name(s):
  • 1.0 Pyruvate[c] + 1.0 Nicotinamide adenine dinucleotide[c] + 1.0 Coenzyme A[c] => 1.0 Nicotinamide adenine dinucleotide - reduced[c] + 1.0 CO2 CO2[c] + 1.0 Acetyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF1354
  • pantograph-l_plantarum_wcfs1
  • pantograph-b_subtilis_subsp_subtilis_str168
• EF1353
  • pantograph-l_plantarum_wcfs1
  • pantograph-b_subtilis_subsp_subtilis_str168
• EF1355
  • pantograph-l_plantarum_wcfs1
  • pantograph-b_subtilis_subsp_subtilis_str168
• EF1356
  • pantograph-l_plantarum_wcfs1
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map01100: map01100
  • 508 reactions found over 2349 reactions in the full pathway
• map01110: map01110
  • 218 reactions found over 1054 reactions in the full pathway
• map01120: map01120
  • 111 reactions found over 715 reactions in the full pathway
• map01200: map01200
  • 50 reactions found over 220 reactions in the full pathway
• map00620: map00620
  • 31 reactions found over 163 reactions in the full pathway
• map00010: map00010
  • 24 reactions found over 149 reactions in the full pathway
• map00020: map00020
  • 9 reactions found over 70 reactions in the full pathway
• map01130: map01130
  • 156 reactions found over 694 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • l_plantarum_wcfs1
    • b_subtilis_subsp_subtilis_str168

External links

• EC Number : 1.2.1
• BioCyc : META:PYRUVDEH-RXN
• MetaNetX (MNX) Equation : MNXR102425
• RHEA:
  • 28042
• Reactome : REACT_R-ATH-71397
• KEGG Reaction : R00209