HMGCOAS

Reaction ADSL2r

• direction:
  • REVERSIBLE
• common name:
  • Adenylosuccinate lyase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 25aics[c] <=> 1.0 aicar[c] + 1.0 fum[c]
• With common name(s):
  • 1.0 (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate[c] <=> 1.0 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide[c] + 1.0 Fumarate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF2361
  • pantograph-l_plantarum_wcfs1
  • pantograph-e_coli_sstr_k12_substr_mg1655
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map00250: map00250
  • 27 reactions found over 93 reactions in the full pathway
• map01130: map01130
  • 156 reactions found over 694 reactions in the full pathway
• map01110: map01110
  • 218 reactions found over 1054 reactions in the full pathway
• map01100: map01100
  • 508 reactions found over 2349 reactions in the full pathway
• map00230: map00230
  • 98 reactions found over 298 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • e_coli_sstr_k12_substr_mg1655
    • l_plantarum_wcfs1
    • b_subtilis_subsp_subtilis_str168

External links

• Reactome : REACT_R-ATH-73800
• MetaNetX (MNX) Equation : MNXR95494
• EC Number : 4.3.2.2
• BioCyc : META:AICARSYN-RXN