EF2858

Reaction IPPS

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 2-isopropylmalate synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 3mob[c] + 1.0 h2o[c] + 1.0 accoa[c] => 1.0 3c3hmp[c] + 1.0 h[c] + 1.0 coa[c]
• With common name(s):
  • 1.0 3-Methyl-2-oxobutanoate[c] + 1.0 H2O H2O[c] + 1.0 Acetyl-CoA[c] => 1.0 3-Carboxy-3-hydroxy-4-methylpentanoate[c] + 1.0 H+[c] + 1.0 Coenzyme A[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF3317
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map01100: map01100
  • 508 reactions found over 2349 reactions in the full pathway
• map01110: map01110
  • 218 reactions found over 1054 reactions in the full pathway
• map00290: map00290
  • 17 reactions found over 49 reactions in the full pathway
• map01210: map01210
  • 25 reactions found over 80 reactions in the full pathway
• map00620: map00620
  • 31 reactions found over 163 reactions in the full pathway
• map01230: map01230
  • 83 reactions found over 228 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • b_subtilis_subsp_subtilis_str168

External links

• RHEA:
  • 21524
• BioCyc : META:2-ISOPROPYLMALATESYN-RXN
• MetaNetX (MNX) Equation : MNXR100879
• KEGG Reaction : R01213
• EC Number : 2.3.3.13