CHORS

Reaction TMPPP

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Thiamine-phosphate diphosphorylase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1.0 4mpetz[c] + 1.0 2mahmp[c] + 1.0 h[c] => 1.0 thmmp[c] + 1.0 ppi[c]
• With common name(s):
  • 1.0 4-Methyl-5-(2-phosphoethyl)-thiazole[c] + 1.0 2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate[c] + 1.0 H+[c] => 1.0 Thiamin monophosphate[c] + 1.0 Diphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EF2776
  • pantograph-l_plantarum_wcfs1
  • pantograph-e_coli_sstr_k12_substr_mg1655
  • pantograph-b_subtilis_subsp_subtilis_str168

Pathways

• map00730: map00730
  • 11 reactions found over 24 reactions in the full pathway
• map01100: map01100
  • 460 reactions found over 2349 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • e_coli_sstr_k12_substr_mg1655
    • l_plantarum_wcfs1
    • b_subtilis_subsp_subtilis_str168

External links

• RHEA:
  • 22328
• BioCyc : META:THI-P-SYN-RXN
• MetaNetX (MNX) Equation : MNXR104908
• KEGG Reaction : R03223
• EC Number : 2.5.1.3