View source for QUINOPRIBOTRANS-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=QUINOPRIBOTRANS-RXN QUINOPRIBOTRANS-RXN] ==
* direction:
** LEFT-TO-RIGHT
* common name:
** nicotinate-nucleotide diphosphorylase (carboxylating)
** quinolinate phosphoribosyltransferase (decarboxylating)
* ec number:
** [http://enzyme.expasy.org/EC/2.4.2.19 EC-2.4.2.19]
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 1 [[PRPP]][c] '''+''' 1 [[QUINOLINATE]][c] '''+''' 2 [[PROTON]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[NICOTINATE_NUCLEOTIDE]][c] '''+''' 1 [[PPI]][c]
* With common name(s):
** 1 5-phospho-&alpha;-D-ribose 1-diphosphate[c] '''+''' 1 quinolinate[c] '''+''' 2 H+[c] '''=>''' 1 CO2[c] '''+''' 1 &beta;-nicotinate D-ribonucleotide[c] '''+''' 1 diphosphate[c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[SJ19144]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
** Source: [[orthology-ectocarpus_siliculosus]]
** Source: [[orthology-nannochloropsis_salina]]
** Source: [[orthology-nannochloropsis_salina]]
** Source: [[orthology-arabidopsis_thaliana]]
* Gene: [[SJ11253]]
** Source: [[orthology-ectocarpus_siliculosus]]
* Gene: [[SJ04451]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
** Source: [[orthology-ectocarpus_siliculosus]]
== Pathways  ==
* [[PWY-5316]], nicotine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5316 PWY-5316]
** '''3''' reactions found over '''9''' reactions in the full pathway
* [[PWY-5653]], NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5653 PWY-5653]
** '''4''' reactions found over '''4''' reactions in the full pathway
* [[PYRIDNUCSYN-PWY]], NAD biosynthesis I (from aspartate): [http://metacyc.org/META/NEW-IMAGE?object=PYRIDNUCSYN-PWY PYRIDNUCSYN-PWY]
** '''6''' reactions found over '''6''' reactions in the full pathway
* [[PWY-7342]], superpathway of nicotine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7342 PWY-7342]
** '''4''' reactions found over '''13''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[orthology]]
** Source: [[orthology-arabidopsis_thaliana]]
*** Tool: [[pantograph]]
** Source: [[orthology-ectocarpus_siliculosus]]
*** Tool: [[pantograph]]
** Source: [[orthology-nannochloropsis_salina]]
*** Tool: [[pantograph]]
* Category: [[annotation]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Tool: [[pathwaytools]]
== External links  ==
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=12733 12733]
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R03348 R03348]
* UNIPROT:
** [http://www.uniprot.org/uniprot/Q9JSX8 Q9JSX8]
** [http://www.uniprot.org/uniprot/Q57916 Q57916]
** [http://www.uniprot.org/uniprot/P30011 P30011]
** [http://www.uniprot.org/uniprot/P46714 P46714]
** [http://www.uniprot.org/uniprot/Q15274 Q15274]
** [http://www.uniprot.org/uniprot/P77938 P77938]
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=nicotinate-nucleotide diphosphorylase (carboxylating)}}
{{#set: common name=quinolinate phosphoribosyltransferase (decarboxylating)}}
{{#set: ec number=EC-2.4.2.19}}
{{#set: gene associated=SJ19144|SJ11253|SJ04451}}
{{#set: in pathway=PWY-5316|PWY-5653|PYRIDNUCSYN-PWY|PWY-7342}}
{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction source=orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus|orthology-nannochloropsis_salina|annotation-saccharina_japonica_genome}}
{{#set: reconstruction tool=pantograph|pathwaytools}}