View source for 3-OXOACYL-ACP-SYNTH-BASE-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-OXOACYL-ACP-SYNTH-BASE-RXN 3-OXOACYL-ACP-SYNTH-BASE-RXN] ==
* direction:
** LEFT-TO-RIGHT
* common name:
** fatty acid synthase
* ec number:
** [http://enzyme.expasy.org/EC/2.3.1.86 EC-2.3.1.86]
** [http://enzyme.expasy.org/EC/2.3.1.85 EC-2.3.1.85]
** [http://enzyme.expasy.org/EC/2.3.1.41 EC-2.3.1.41]
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 1 [[PROTON]][c] '''+''' 1 [[ACETYL-ACP]][c] '''+''' 1 [[MALONYL-ACP]][c] '''=>''' 1 [[Acetoacetyl-ACPs]][c] '''+''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[ACP]][c]
* With common name(s):
** 1 H+[c] '''+''' 1 an acetyl-[acp][c] '''+''' 1 a malonyl-[acp][c] '''=>''' 1 an acetoacetyl-[acp][c] '''+''' 1 CO2[c] '''+''' 1 a holo-[acyl-carrier protein][c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[SJ06616]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ00613]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ06617]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ06944]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ15983]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
** Source: [[orthology-ectocarpus_siliculosus]]
** Source: [[orthology-arabidopsis_thaliana]]
** Source: [[orthology-arabidopsis_thaliana]]
* Gene: [[SJ11672]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ18059]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ15984]]
** Source: [[orthology-ectocarpus_siliculosus]]
** Source: [[orthology-nannochloropsis_salina]]
* Gene: [[SJ04769]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ13014]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ19629]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ04443]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
** Source: [[orthology-ectocarpus_siliculosus]]
** Source: [[orthology-nannochloropsis_salina]]
** Source: [[orthology-arabidopsis_thaliana]]
** Source: [[orthology-arabidopsis_thaliana]]
* Gene: [[SJ10624]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ00320]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ00005]]
** Source: [[orthology-ectocarpus_siliculosus]]
* Gene: [[SJ03883]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
* Gene: [[SJ17743]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
== Pathways  ==
* [[PWY-5965]], fatty acid biosynthesis initiation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5965 PWY-5965]
** '''1''' reactions found over '''2''' reactions in the full pathway
* [[PWY-5966]], fatty acid biosynthesis initiation II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5966 PWY-5966]
** '''2''' reactions found over '''2''' reactions in the full pathway
* [[FASYN-INITIAL-PWY]], superpathway of fatty acid biosynthesis initiation (E. coli): [http://metacyc.org/META/NEW-IMAGE?object=FASYN-INITIAL-PWY FASYN-INITIAL-PWY]
** '''5''' reactions found over '''8''' reactions in the full pathway
* [[PWY-7388]], octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7388 PWY-7388]
** '''9''' reactions found over '''9''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[orthology]]
** Source: [[orthology-arabidopsis_thaliana]]
*** Tool: [[pantograph]]
** Source: [[orthology-ectocarpus_siliculosus]]
*** Tool: [[pantograph]]
** Source: [[orthology-nannochloropsis_salina]]
*** Tool: [[pantograph]]
* Category: [[annotation]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Tool: [[pathwaytools]]
== External links  ==
* UNIPROT:
** [http://www.uniprot.org/uniprot/P23902 P23902]
** [http://www.uniprot.org/uniprot/P0A6R0 P0A6R0]
** [http://www.uniprot.org/uniprot/P49327 P49327]
** [http://www.uniprot.org/uniprot/P43710 P43710]
** [http://www.uniprot.org/uniprot/Q9HYR2 Q9HYR2]
** [http://www.uniprot.org/uniprot/O67612 O67612]
** [http://www.uniprot.org/uniprot/P20582 P20582]
** [http://www.uniprot.org/uniprot/Q9JT63 Q9JT63]
** [http://www.uniprot.org/uniprot/Q9JW56 Q9JW56]
** [http://www.uniprot.org/uniprot/Q9PMZ6 Q9PMZ6]
** [http://www.uniprot.org/uniprot/P43711 P43711]
** [http://www.uniprot.org/uniprot/O25284 O25284]
** [http://www.uniprot.org/uniprot/Q9JX65 Q9JX65]
** [http://www.uniprot.org/uniprot/O34340 O34340]
** [http://www.uniprot.org/uniprot/Q9PI63 Q9PI63]
** [http://www.uniprot.org/uniprot/P0AAI5 P0AAI5]
** [http://www.uniprot.org/uniprot/Q07510 Q07510]
** [http://www.uniprot.org/uniprot/Q06097 Q06097]
** [http://www.uniprot.org/uniprot/P41175 P41175]
** [http://www.uniprot.org/uniprot/P31176 P31176]
** [http://www.uniprot.org/uniprot/Q40027 Q40027]
** [http://www.uniprot.org/uniprot/Q40028 Q40028]
** [http://www.uniprot.org/uniprot/P73283 P73283]
** [http://www.uniprot.org/uniprot/P0A953 P0A953]
** [http://www.uniprot.org/uniprot/O64485 O64485]
** [http://www.uniprot.org/uniprot/O65677 O65677]
** [http://www.uniprot.org/uniprot/Q39310 Q39310]
** [http://www.uniprot.org/uniprot/O23738 O23738]
** [http://www.uniprot.org/uniprot/Q41134 Q41134]
** [http://www.uniprot.org/uniprot/Q41135 Q41135]
** [http://www.uniprot.org/uniprot/Q54208 Q54208]
** [http://www.uniprot.org/uniprot/O54440 O54440]
** [http://www.uniprot.org/uniprot/P55338 P55338]
** [http://www.uniprot.org/uniprot/Q9RA31 Q9RA31]
** [http://www.uniprot.org/uniprot/P12276 P12276]
** [http://www.uniprot.org/uniprot/P12785 P12785]
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=fatty acid synthase}}
{{#set: ec number=EC-2.3.1.86}}
{{#set: ec number=EC-2.3.1.85}}
{{#set: ec number=EC-2.3.1.41}}
{{#set: gene associated=SJ06616|SJ00613|SJ06617|SJ06944|SJ15983|SJ11672|SJ18059|SJ15984|SJ04769|SJ13014|SJ19629|SJ04443|SJ10624|SJ00320|SJ00005|SJ03883|SJ17743}}
{{#set: in pathway=PWY-5965|PWY-5966|FASYN-INITIAL-PWY|PWY-7388}}
{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction source=orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus|orthology-nannochloropsis_salina|annotation-saccharina_japonica_genome}}
{{#set: reconstruction tool=pantograph|pathwaytools}}