View source for ESTRADIOL-17-BETA-DEHYDROGENASE-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=ESTRADIOL-17-BETA-DEHYDROGENASE-RXN ESTRADIOL-17-BETA-DEHYDROGENASE-RXN] ==
* direction:
** LEFT-TO-RIGHT
* ec number:
** [http://enzyme.expasy.org/EC/1.1.1.62 EC-1.1.1.62]
* common name:
** estradiol-17&beta; dehydrogenase / estrone reductase
** estradiol 17-beta-dehydrogenase
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 1 [[ESTRONE]][c] '''+''' 1 [[NADH-P-OR-NOP]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CPD-352]][c] '''+''' 1 [[NAD-P-OR-NOP]][c]
* With common name(s):
** 1 estrone[c] '''+''' 1 NAD(P)H[c] '''+''' 1 H+[c] '''=>''' 1 17&beta;-estradiol[c] '''+''' 1 NAD(P)+[c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[SJ10028]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ20291]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ05275]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ05276]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ05277]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ21322]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ06969]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ21312]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: EC-NUMBER
* Gene: [[SJ01444]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Assignment: GO-TERM
== Pathways  ==
* [[PWY66-380]], estradiol biosynthesis I (via estrone): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-380 PWY66-380]
** '''1''' reactions found over '''4''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[annotation]]
** Source: [[annotation-saccharina_japonica_genome]]
*** Tool: [[pathwaytools]]
== External links  ==
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24618 24618]
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24615 24615]
* UNIPROT:
** [http://www.uniprot.org/uniprot/P37059 P37059]
** [http://www.uniprot.org/uniprot/P70694 P70694]
** [http://www.uniprot.org/uniprot/P14061 P14061]
** [http://www.uniprot.org/uniprot/P37058 P37058]
** [http://www.uniprot.org/uniprot/P51657 P51657]
** [http://www.uniprot.org/uniprot/P51659 P51659]
** [http://www.uniprot.org/uniprot/P51656 P51656]
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: ec number=EC-1.1.1.62}}
{{#set: common name=estradiol-17&beta; dehydrogenase / estrone reductase}}
{{#set: common name=estradiol 17-beta-dehydrogenase}}
{{#set: gene associated=SJ10028|SJ20291|SJ05275|SJ05276|SJ05277|SJ21322|SJ06969|SJ21312|SJ01444}}
{{#set: in pathway=PWY66-380}}
{{#set: reconstruction category=annotation}}
{{#set: reconstruction source=annotation-saccharina_japonica_genome}}
{{#set: reconstruction tool=pathwaytools}}