Difference between revisions of "1.1.1.34-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.1.1.34-RXN 1.1.1.34-RXN] == * direction: ** REVERSIBLE * common name: ** hydroxymethylglutaryl-Co...")
 
 
Line 3: Line 3:
 
* direction:
 
* direction:
 
** REVERSIBLE
 
** REVERSIBLE
−
* common name:
 
−
** hydroxymethylglutaryl-CoA reductase
 
 
* ec number:
 
* ec number:
 
** [http://enzyme.expasy.org/EC/1.1.1.34 EC-1.1.1.34]
 
** [http://enzyme.expasy.org/EC/1.1.1.34 EC-1.1.1.34]
 +
* common name:
 +
** hydroxymethylglutaryl-CoA reductase
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[MEVALONATE]][c] '''+''' 2 [[NADP]][c] '''+''' 1 [[CO-A]][c] '''<=>''' 2 [[PROTON]][c] '''+''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 2 [[NADPH]][c]
+
** 2 [[NADP]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[MEVALONATE]][c] '''<=>''' 2 [[PROTON]][c] '''+''' 2 [[NADPH]][c] '''+''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 (R)-mevalonate[c] '''+''' 2 NADP+[c] '''+''' 1 coenzyme A[c] '''<=>''' 2 H+[c] '''+''' 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''+''' 2 NADPH[c]
+
** 2 NADP+[c] '''+''' 1 coenzyme A[c] '''+''' 1 (R)-mevalonate[c] '''<=>''' 2 H+[c] '''+''' 2 NADPH[c] '''+''' 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[SJ18779]]
+
* Gene: [[SJ18136]]
−
** Source: [[annotation-saccharina_japonica_genome]]
+
−
*** Assignment: EC-NUMBER
+
 
** Source: [[orthology-ectocarpus_siliculosus]]
 
** Source: [[orthology-ectocarpus_siliculosus]]
−
** Source: [[orthology-arabidopsis_thaliana]]
 
 
* Gene: [[SJ05150]]
 
* Gene: [[SJ05150]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
** Source: [[orthology-ectocarpus_siliculosus]]
 
** Source: [[orthology-ectocarpus_siliculosus]]
−
* Gene: [[SJ18136]]
+
* Gene: [[SJ18779]]
 +
** Source: [[annotation-saccharina_japonica_genome]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-arabidopsis_thaliana]]
 
** Source: [[orthology-ectocarpus_siliculosus]]
 
** Source: [[orthology-ectocarpus_siliculosus]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-922]], mevalonate pathway I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-922 PWY-922]
 
−
** '''7''' reactions found over '''7''' reactions in the full pathway
 
 
* [[PWY-6174]], mevalonate pathway II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6174 PWY-6174]
 
* [[PWY-6174]], mevalonate pathway II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6174 PWY-6174]
 
** '''6''' reactions found over '''7''' reactions in the full pathway
 
** '''6''' reactions found over '''7''' reactions in the full pathway
−
* [[PWY-7391]], isoprene biosynthesis II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7391 PWY-7391]
+
* [[PWY-922]], mevalonate pathway I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-922 PWY-922]
−
** '''7''' reactions found over '''8''' reactions in the full pathway
+
** '''7''' reactions found over '''7''' reactions in the full pathway
 
* [[PWY-7524]], mevalonate pathway III (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7524 PWY-7524]
 
* [[PWY-7524]], mevalonate pathway III (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7524 PWY-7524]
 
** '''5''' reactions found over '''8''' reactions in the full pathway
 
** '''5''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-7391]], isoprene biosynthesis II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7391 PWY-7391]
 +
** '''7''' reactions found over '''8''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
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== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15989 15989]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15992 15992]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
 
** [http://www.genome.jp/dbget-bin/www_bget?R02082 R02082]
 
** [http://www.genome.jp/dbget-bin/www_bget?R02082 R02082]
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** [http://www.uniprot.org/uniprot/O08424 O08424]
 
** [http://www.uniprot.org/uniprot/O08424 O08424]
 
{{#set: direction=REVERSIBLE}}
 
{{#set: direction=REVERSIBLE}}
−
{{#set: common name=hydroxymethylglutaryl-CoA reductase}}
 
 
{{#set: ec number=EC-1.1.1.34}}
 
{{#set: ec number=EC-1.1.1.34}}
−
{{#set: gene associated=SJ18779|SJ05150|SJ18136}}
+
{{#set: common name=hydroxymethylglutaryl-CoA reductase}}
−
{{#set: in pathway=PWY-922|PWY-6174|PWY-7391|PWY-7524}}
+
{{#set: gene associated=SJ18136|SJ05150|SJ18779}}
 +
{{#set: in pathway=PWY-6174|PWY-922|PWY-7524|PWY-7391}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction source=orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus|annotation-saccharina_japonica_genome}}
+
{{#set: reconstruction source=orthology-arabidopsis_thaliana|annotation-saccharina_japonica_genome|orthology-ectocarpus_siliculosus}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 13:22, 10 January 2019

Reaction 1.1.1.34-RXN

  • direction:
    • REVERSIBLE
  • ec number:
  • common name:
    • hydroxymethylglutaryl-CoA reductase
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6174, mevalonate pathway II (archaea): PWY-6174
    • 6 reactions found over 7 reactions in the full pathway
  • PWY-922, mevalonate pathway I: PWY-922
    • 7 reactions found over 7 reactions in the full pathway
  • PWY-7524, mevalonate pathway III (archaea): PWY-7524
    • 5 reactions found over 8 reactions in the full pathway
  • PWY-7391, isoprene biosynthesis II (engineered): PWY-7391
    • 7 reactions found over 8 reactions in the full pathway

Reconstruction information

External links





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