Difference between revisions of "2.4.1.225-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.4.1.225-RXN 2.4.1.225-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** N-acetylglucosaminy...")
 
 
Line 3: Line 3:
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
−
* common name:
 
−
** N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase
 
 
* ec number:
 
* ec number:
 
** [http://enzyme.expasy.org/EC/2.4.1.225 EC-2.4.1.225]
 
** [http://enzyme.expasy.org/EC/2.4.1.225 EC-2.4.1.225]
 +
* common name:
 +
** N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[UDP-GLUCURONATE]][c] '''+''' 1 [[GlcNAc-GlcA-Gal-Gal-Xyl-Protein]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[GlcA-GlcNAc-GlcA-Gal-Gal-Xyl-Protein]][c] '''+''' 1 [[UDP]][c]
+
** 1 [[UDP-GLUCURONATE]][c] '''+''' 1 [[GlcNAc-GlcA-Gal-Gal-Xyl-Protein]][c] '''=>''' 1 [[GlcA-GlcNAc-GlcA-Gal-Gal-Xyl-Protein]][c] '''+''' 1 [[UDP]][c] '''+''' 1 [[PROTON]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 UDP-α-D-glucuronate[c] '''+''' 1 a [protein]-3-O-(α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] '''=>''' 1 H+[c] '''+''' 1 a [protein]-3-O-(β-D-GlcA-(1→3)-α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] '''+''' 1 UDP[c]
+
** 1 UDP-α-D-glucuronate[c] '''+''' 1 a [protein]-3-O-(α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] '''=>''' 1 a [protein]-3-O-(β-D-GlcA-(1→3)-α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] '''+''' 1 UDP[c] '''+''' 1 H+[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[SJ14192]]
+
* Gene: [[SJ11522]]
 +
** Source: [[annotation-saccharina_japonica_genome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[SJ01052]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
Line 26: Line 29:
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[SJ11522]]
+
* Gene: [[SJ08296]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[SJ01052]]
+
* Gene: [[SJ14184]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[SJ07780]]
+
* Gene: [[SJ14192]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[SJ08296]]
+
* Gene: [[SJ07780]]
−
** Source: [[annotation-saccharina_japonica_genome]]
+
−
*** Assignment: EC-NUMBER
+
−
* Gene: [[SJ14184]]
+
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
Line 49: Line 49:
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 +
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=20909 20909]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
 
** [http://www.genome.jp/dbget-bin/www_bget?R07335 R07335]
 
** [http://www.genome.jp/dbget-bin/www_bget?R07335 R07335]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: common name=N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase}}
 
 
{{#set: ec number=EC-2.4.1.225}}
 
{{#set: ec number=EC-2.4.1.225}}
−
{{#set: gene associated=SJ14192|SJ08300|SJ08295|SJ11522|SJ01052|SJ07780|SJ08296|SJ14184}}
+
{{#set: common name=N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase}}
 +
{{#set: gene associated=SJ11522|SJ01052|SJ08300|SJ08295|SJ08296|SJ14184|SJ14192|SJ07780}}
 
{{#set: in pathway=PWY-6558}}
 
{{#set: in pathway=PWY-6558}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-saccharina_japonica_genome}}
 
{{#set: reconstruction source=annotation-saccharina_japonica_genome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 15:22, 10 January 2019

Reaction 2.4.1.225-RXN

  • direction:
    • LEFT-TO-RIGHT
  • ec number:
  • common name:
    • N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 UDP-α-D-glucuronate[c] + 1 a [protein]-3-O-(α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] => 1 a [protein]-3-O-(β-D-GlcA-(1→3)-α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] + 1 UDP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6558, heparan sulfate biosynthesis (late stages): PWY-6558
    • 7 reactions found over 13 reactions in the full pathway

Reconstruction information

External links





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