Difference between revisions of "MALATE-DEH-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=MALATE-DEH-RXN MALATE-DEH-RXN] == * direction: ** REVERSIBLE * common name: ** malate dehydrogenase...")
 
 
Line 3: Line 3:
 
* direction:
 
* direction:
 
** REVERSIBLE
 
** REVERSIBLE
−
* common name:
 
−
** malate dehydrogenase
 
 
* ec number:
 
* ec number:
 
** [http://enzyme.expasy.org/EC/1.1.1.37 EC-1.1.1.37]
 
** [http://enzyme.expasy.org/EC/1.1.1.37 EC-1.1.1.37]
 +
* common name:
 +
** malate dehydrogenase
 
* Synonym(s):
 
* Synonym(s):
 
** malate dehydrogenation
 
** malate dehydrogenation
Line 12: Line 12:
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[MAL]][c] '''+''' 1 [[NAD]][c] '''<=>''' 1 [[PROTON]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[OXALACETIC_ACID]][c]
+
** 1 [[NAD]][c] '''+''' 1 [[MAL]][c] '''<=>''' 1 [[PROTON]][c] '''+''' 1 [[OXALACETIC_ACID]][c] '''+''' 1 [[NADH]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 (S)-malate[c] '''+''' 1 NAD+[c] '''<=>''' 1 H+[c] '''+''' 1 NADH[c] '''+''' 1 oxaloacetate[c]
+
** 1 NAD+[c] '''+''' 1 (S)-malate[c] '''<=>''' 1 H+[c] '''+''' 1 oxaloacetate[c] '''+''' 1 NADH[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[SJ15523]]
+
* Gene: [[SJ15746]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
** Source: [[orthology-nannochloropsis_salina]]
 
** Source: [[orthology-nannochloropsis_salina]]
 +
** Source: [[orthology-arabidopsis_thaliana]]
 +
** Source: [[orthology-arabidopsis_thaliana]]
 +
** Source: [[orthology-arabidopsis_thaliana]]
 +
** Source: [[orthology-arabidopsis_thaliana]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 
* Gene: [[SJ05075]]
 
* Gene: [[SJ05075]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
** Source: [[orthology-ectocarpus_siliculosus]]
 
 
** Source: [[orthology-nannochloropsis_salina]]
 
** Source: [[orthology-nannochloropsis_salina]]
 
** Source: [[orthology-nannochloropsis_salina]]
 
** Source: [[orthology-nannochloropsis_salina]]
Line 32: Line 36:
 
** Source: [[orthology-arabidopsis_thaliana]]
 
** Source: [[orthology-arabidopsis_thaliana]]
 
** Source: [[orthology-arabidopsis_thaliana]]
 
** Source: [[orthology-arabidopsis_thaliana]]
−
* Gene: [[SJ15746]]
+
** Source: [[orthology-ectocarpus_siliculosus]]
 +
* Gene: [[SJ15523]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
** Source: [[annotation-saccharina_japonica_genome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
** Source: [[orthology-ectocarpus_siliculosus]]
 
 
** Source: [[orthology-nannochloropsis_salina]]
 
** Source: [[orthology-nannochloropsis_salina]]
−
** Source: [[orthology-arabidopsis_thaliana]]
 
−
** Source: [[orthology-arabidopsis_thaliana]]
 
−
** Source: [[orthology-arabidopsis_thaliana]]
 
−
** Source: [[orthology-arabidopsis_thaliana]]
 
 
== Pathways  ==
 
== Pathways  ==
 +
* [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
 +
** '''9''' reactions found over '''10''' reactions in the full pathway
 +
* [[P108-PWY]], pyruvate fermentation to propanoate I: [http://metacyc.org/META/NEW-IMAGE?object=P108-PWY P108-PWY]
 +
** '''2''' reactions found over '''7''' reactions in the full pathway
 
* [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY]
 
* [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY]
 
** '''11''' reactions found over '''16''' reactions in the full pathway
 
** '''11''' reactions found over '''16''' reactions in the full pathway
 +
* [[PWY-7115]], C4 photosynthetic carbon assimilation cycle, NAD-ME type: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7115 PWY-7115]
 +
** '''9''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
 +
** '''11''' reactions found over '''19''' reactions in the full pathway
 
* [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
 
* [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
 
** '''10''' reactions found over '''11''' reactions in the full pathway
 
** '''10''' reactions found over '''11''' reactions in the full pathway
−
* [[PWY-561]], superpathway of glyoxylate cycle and fatty acid degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-561 PWY-561]
+
* [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392]
−
** '''6''' reactions found over '''8''' reactions in the full pathway
+
** '''6''' reactions found over '''12''' reactions in the full pathway
−
* [[MALATE-ASPARTATE-SHUTTLE-PWY]], L-aspartate degradation II: [http://metacyc.org/META/NEW-IMAGE?object=MALATE-ASPARTATE-SHUTTLE-PWY MALATE-ASPARTATE-SHUTTLE-PWY]
+
−
** '''2''' reactions found over '''2''' reactions in the full pathway
+
−
* [[PWY-1622]], formaldehyde assimilation I (serine pathway): [http://metacyc.org/META/NEW-IMAGE?object=PWY-1622 PWY-1622]
+
−
** '''7''' reactions found over '''13''' reactions in the full pathway
+
 
* [[GLUCONEO-PWY]], gluconeogenesis I: [http://metacyc.org/META/NEW-IMAGE?object=GLUCONEO-PWY GLUCONEO-PWY]
 
* [[GLUCONEO-PWY]], gluconeogenesis I: [http://metacyc.org/META/NEW-IMAGE?object=GLUCONEO-PWY GLUCONEO-PWY]
−
** '''13''' reactions found over '''13''' reactions in the full pathway
+
** '''12''' reactions found over '''13''' reactions in the full pathway
−
* [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
+
−
** '''5''' reactions found over '''7''' reactions in the full pathway
+
 
* [[PWY-7383]], anaerobic energy metabolism (invertebrates, cytosol): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7383 PWY-7383]
 
* [[PWY-7383]], anaerobic energy metabolism (invertebrates, cytosol): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7383 PWY-7383]
−
** '''5''' reactions found over '''7''' reactions in the full pathway
+
** '''4''' reactions found over '''7''' reactions in the full pathway
−
* [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392]
+
−
** '''6''' reactions found over '''12''' reactions in the full pathway
+
 
* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
 
* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
 
** '''10''' reactions found over '''11''' reactions in the full pathway
 
** '''10''' reactions found over '''11''' reactions in the full pathway
 +
* [[MALATE-ASPARTATE-SHUTTLE-PWY]], L-aspartate degradation II: [http://metacyc.org/META/NEW-IMAGE?object=MALATE-ASPARTATE-SHUTTLE-PWY MALATE-ASPARTATE-SHUTTLE-PWY]
 +
** '''2''' reactions found over '''2''' reactions in the full pathway
 
* [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
 
* [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
−
** '''10''' reactions found over '''12''' reactions in the full pathway
+
** '''9''' reactions found over '''12''' reactions in the full pathway
 +
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
 +
** '''10''' reactions found over '''11''' reactions in the full pathway
 +
* [[GLYOXYLATE-BYPASS]], glyoxylate cycle: [http://metacyc.org/META/NEW-IMAGE?object=GLYOXYLATE-BYPASS GLYOXYLATE-BYPASS]
 +
** '''6''' reactions found over '''6''' reactions in the full pathway
 +
* [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
 +
** '''5''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-561]], superpathway of glyoxylate cycle and fatty acid degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-561 PWY-561]
 +
** '''6''' reactions found over '''8''' reactions in the full pathway
 
* [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
 
* [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
 
** '''8''' reactions found over '''9''' reactions in the full pathway
 
** '''8''' reactions found over '''9''' reactions in the full pathway
−
* [[GLYOXYLATE-BYPASS]], glyoxylate cycle: [http://metacyc.org/META/NEW-IMAGE?object=GLYOXYLATE-BYPASS GLYOXYLATE-BYPASS]
 
−
** '''6''' reactions found over '''6''' reactions in the full pathway
 
 
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
 
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
 
** '''10''' reactions found over '''12''' reactions in the full pathway
 
** '''10''' reactions found over '''12''' reactions in the full pathway
−
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
 
−
** '''11''' reactions found over '''18''' reactions in the full pathway
 
−
* [[PWY-7115]], C4 photosynthetic carbon assimilation cycle, NAD-ME type: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7115 PWY-7115]
 
−
** '''9''' reactions found over '''9''' reactions in the full pathway
 
−
* [[P108-PWY]], pyruvate fermentation to propanoate I: [http://metacyc.org/META/NEW-IMAGE?object=P108-PWY P108-PWY]
 
−
** '''2''' reactions found over '''7''' reactions in the full pathway
 
 
* [[PWY66-399]], gluconeogenesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-399 PWY66-399]
 
* [[PWY66-399]], gluconeogenesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-399 PWY66-399]
 
** '''11''' reactions found over '''12''' reactions in the full pathway
 
** '''11''' reactions found over '''12''' reactions in the full pathway
−
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
+
* [[PWY-1622]], formaldehyde assimilation I (serine pathway): [http://metacyc.org/META/NEW-IMAGE?object=PWY-1622 PWY-1622]
−
** '''10''' reactions found over '''11''' reactions in the full pathway
+
** '''6''' reactions found over '''13''' reactions in the full pathway
−
* [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
+
−
** '''9''' reactions found over '''10''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
 
** Source: [[orthology-arabidopsis_thaliana]]
 
** Source: [[orthology-arabidopsis_thaliana]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-nannochloropsis_salina]]
 
*** Tool: [[pantograph]]
 
*** Tool: [[pantograph]]
 
** Source: [[orthology-ectocarpus_siliculosus]]
 
** Source: [[orthology-ectocarpus_siliculosus]]
−
*** Tool: [[pantograph]]
 
−
** Source: [[orthology-nannochloropsis_salina]]
 
 
*** Tool: [[pantograph]]
 
*** Tool: [[pantograph]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
Line 95: Line 95:
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21432 21432]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21435 21435]
 +
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R00342 R00342]
 
* PIR:
 
* PIR:
 
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A32472 A32472]
 
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A32472 A32472]
Line 157: Line 159:
 
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T51311 T51311]
 
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T51311 T51311]
 
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T51862 T51862]
 
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T51862 T51862]
−
* LIGAND-RXN:
 
−
** [http://www.genome.jp/dbget-bin/www_bget?R00342 R00342]
 
 
* UNIPROT:
 
* UNIPROT:
 
** [http://www.uniprot.org/uniprot/Q07841 Q07841]
 
** [http://www.uniprot.org/uniprot/Q07841 Q07841]
Line 216: Line 216:
 
** [http://www.uniprot.org/uniprot/Q9SN86 Q9SN86]
 
** [http://www.uniprot.org/uniprot/Q9SN86 Q9SN86]
 
{{#set: direction=REVERSIBLE}}
 
{{#set: direction=REVERSIBLE}}
−
{{#set: common name=malate dehydrogenase}}
 
 
{{#set: ec number=EC-1.1.1.37}}
 
{{#set: ec number=EC-1.1.1.37}}
 +
{{#set: common name=malate dehydrogenase}}
 
{{#set: common name=malate dehydrogenation}}
 
{{#set: common name=malate dehydrogenation}}
−
{{#set: gene associated=SJ15523|SJ05075|SJ15746}}
+
{{#set: gene associated=SJ15746|SJ05075|SJ15523}}
−
{{#set: in pathway=FERMENTATION-PWY|PWY-5913|PWY-561|MALATE-ASPARTATE-SHUTTLE-PWY|PWY-1622|GLUCONEO-PWY|P42-PWY|PWY-7383|PWY-5392|P105-PWY|P23-PWY|PWY-5690|GLYOXYLATE-BYPASS|PWY-6969|PWY-6728|PWY-7115|P108-PWY|PWY66-399|PWY66-398|TCA}}
+
{{#set: in pathway=TCA|P108-PWY|FERMENTATION-PWY|PWY-7115|PWY-6728|PWY-5913|PWY-5392|GLUCONEO-PWY|PWY-7383|P105-PWY|MALATE-ASPARTATE-SHUTTLE-PWY|P23-PWY|PWY66-398|GLYOXYLATE-BYPASS|P42-PWY|PWY-561|PWY-5690|PWY-6969|PWY66-399|PWY-1622}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction source=orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus|orthology-nannochloropsis_salina|annotation-saccharina_japonica_genome}}
+
{{#set: reconstruction source=orthology-arabidopsis_thaliana|annotation-saccharina_japonica_genome|orthology-nannochloropsis_salina|orthology-ectocarpus_siliculosus}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 14:19, 10 January 2019

Reaction MALATE-DEH-RXN

  • direction:
    • REVERSIBLE
  • ec number:
  • common name:
    • malate dehydrogenase
  • Synonym(s):
    • malate dehydrogenation

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NAD+[c] + 1 (S)-malate[c] <=> 1 H+[c] + 1 oxaloacetate[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • TCA, TCA cycle I (prokaryotic): TCA
    • 9 reactions found over 10 reactions in the full pathway
  • P108-PWY, pyruvate fermentation to propanoate I: P108-PWY
    • 2 reactions found over 7 reactions in the full pathway
  • FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
    • 11 reactions found over 16 reactions in the full pathway
  • PWY-7115, C4 photosynthetic carbon assimilation cycle, NAD-ME type: PWY-7115
    • 9 reactions found over 9 reactions in the full pathway
  • PWY-6728, methylaspartate cycle: PWY-6728
    • 11 reactions found over 19 reactions in the full pathway
  • PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
    • 10 reactions found over 11 reactions in the full pathway
  • PWY-5392, reductive TCA cycle II: PWY-5392
    • 6 reactions found over 12 reactions in the full pathway
  • GLUCONEO-PWY, gluconeogenesis I: GLUCONEO-PWY
    • 12 reactions found over 13 reactions in the full pathway
  • PWY-7383, anaerobic energy metabolism (invertebrates, cytosol): PWY-7383
    • 4 reactions found over 7 reactions in the full pathway
  • P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
    • 10 reactions found over 11 reactions in the full pathway
  • MALATE-ASPARTATE-SHUTTLE-PWY, L-aspartate degradation II: MALATE-ASPARTATE-SHUTTLE-PWY
    • 2 reactions found over 2 reactions in the full pathway
  • P23-PWY, reductive TCA cycle I: P23-PWY
    • 9 reactions found over 12 reactions in the full pathway
  • PWY66-398, TCA cycle III (animals): PWY66-398
    • 10 reactions found over 11 reactions in the full pathway
  • GLYOXYLATE-BYPASS, glyoxylate cycle: GLYOXYLATE-BYPASS
    • 6 reactions found over 6 reactions in the full pathway
  • P42-PWY, incomplete reductive TCA cycle: P42-PWY
    • 5 reactions found over 7 reactions in the full pathway
  • PWY-561, superpathway of glyoxylate cycle and fatty acid degradation: PWY-561
    • 6 reactions found over 8 reactions in the full pathway
  • PWY-5690, TCA cycle II (plants and fungi): PWY-5690
    • 8 reactions found over 9 reactions in the full pathway
  • PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
    • 10 reactions found over 12 reactions in the full pathway
  • PWY66-399, gluconeogenesis III: PWY66-399
    • 11 reactions found over 12 reactions in the full pathway
  • PWY-1622, formaldehyde assimilation I (serine pathway): PWY-1622
    • 6 reactions found over 13 reactions in the full pathway

Reconstruction information

External links





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