RXN-7682

Reaction RXN-7682

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-1.17.1.4
• common name:
  • hypoxanthine hydroxylase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 HYPOXANTHINE[c] + 1 NAD[c] + 1 WATER[c] => 1 XANTHINE[c] + 1 NADH[c] + 1 PROTON[c]
• With common name(s):
  • 1 hypoxanthine[c] + 1 NAD+[c] + 1 H2O[c] => 1 xanthine[c] + 1 NADH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ05673
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ05668
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ13098
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-arabidopsis_thaliana
• Gene: SJ13101
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ05674
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ13100
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ13095
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ05660
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• P164-PWY, purine nucleobases degradation I (anaerobic): P164-PWY
  • 6 reactions found over 17 reactions in the full pathway
• PWY-6596, adenosine nucleotides degradation I: PWY-6596
  • 7 reactions found over 8 reactions in the full pathway
• SALVADEHYPOX-PWY, adenosine nucleotides degradation II: SALVADEHYPOX-PWY
  • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 24671
• LIGAND-RXN:
  • R01768