5-FORMYL-THF-CYCLO-LIGASE-RXN

Reaction 5-FORMYL-THF-CYCLO-LIGASE-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-6.3.3.2
• common name:
  • 5-formyltetrahydrofolate cyclo-ligase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 N5-Formyl-THF-Glu-N[c] + 1 ATP[c] => 1 5-10-METHENYL-THF-GLU-N[c] + 1 ADP[c] + 1 Pi[c]
• With common name(s):
  • 1 an (6S)-N5-formyl-tetrahydrofolate[c] + 1 ATP[c] => 1 a 5,10-methenyltetrahydrofolate[c] + 1 ADP[c] + 1 phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ02064
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ19600
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
  • 8 reactions found over 9 reactions in the full pathway
• PWY-3841, folate transformations II: PWY-3841
  • 9 reactions found over 11 reactions in the full pathway
• PWY-2201, folate transformations I: PWY-2201
  • 9 reactions found over 12 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 10489
• LIGAND-RXN:
  • R02301
• UNIPROT:
  • P80405
  • P49914