GTP-CYCLOHYDRO-I-RXN

Reaction GTP-CYCLOHYDRO-I-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-3.5.4.16
• common name:
  • GTP cyclohydrolase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GTP[c] + 1 WATER[c] => 1 PROTON[c] + 1 FORMATE[c] + 1 DIHYDRONEOPTERIN-P3[c]
• With common name(s):
  • 1 GTP[c] + 1 H2O[c] => 1 H+[c] + 1 formate[c] + 1 7,8-dihydroneopterin 3'-triphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ00877
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-7852, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium): PWY-7852
  • 2 reactions found over 3 reactions in the full pathway
• PWY-5664, erythro-tetrahydrobiopterin biosynthesis II: PWY-5664
  • 2 reactions found over 4 reactions in the full pathway
• PWY0-1433, tetrahydromonapterin biosynthesis: PWY0-1433
  • 1 reactions found over 4 reactions in the full pathway
• PWY-5663, erythro-tetrahydrobiopterin biosynthesis I: PWY-5663
  • 3 reactions found over 3 reactions in the full pathway
• PWY-7442, drosopterin and aurodrosopterin biosynthesis: PWY-7442
  • 3 reactions found over 7 reactions in the full pathway
• PWY-6983, threo-tetrahydrobiopterin biosynthesis: PWY-6983
  • 2 reactions found over 3 reactions in the full pathway
• PWY-6147, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I: PWY-6147
  • 5 reactions found over 5 reactions in the full pathway
• PWY-6703, preQ0 biosynthesis: PWY-6703
  • 1 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 17473
• LIGAND-RXN:
  • R00424
• UNIPROT:
  • P19465
  • P22288
  • P43866
  • P51594
  • P64207
  • Q9CGE3
  • O66603
  • P56462
  • P0A6T5
  • P50141
  • P30793
  • P51601
  • Q05915
  • P51597
  • P51600
  • Q94465
  • Q55759