DIHYDROFOLATESYNTH-RXN

Reaction DIHYDROFOLATESYNTH-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-6.3.2.12
• common name:
  • dihydrofolate synthetase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GLT[c] + 1 7-8-DIHYDROPTEROATE[c] + 1 ATP[c] => 1 PROTON[c] + 1 DIHYDROFOLATE[c] + 1 Pi[c] + 1 ADP[c]
• With common name(s):
  • 1 L-glutamate[c] + 1 7,8-dihydropteroate[c] + 1 ATP[c] => 1 H+[c] + 1 7,8-dihydrofolate monoglutamate[c] + 1 phosphate[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ17018
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-6614, tetrahydrofolate biosynthesis: PWY-6614
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 23585
• LIGAND-RXN:
  • R02237
• UNIPROT:
  • Q9JVC6
  • P43775
  • Q9PNK6
  • Q50990
  • P08192