GLUTAMIDOTRANS-RXN

Reaction GLUTAMIDOTRANS-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-4.3.2.M2
• common name:
  • imidazoleglycerol-phosphate synthase
• Synonym(s):
  • imidazole glycerol phosphate synthase cyclase subunit
  • Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
  • Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)

Reaction Formula

• With identifiers:
  • 1 PHOSPHORIBULOSYL-FORMIMINO-AICAR-P[c] + 1 GLN[c] => 1 PROTON[c] + 1 GLT[c] + 1 D-ERYTHRO-IMIDAZOLE-GLYCEROL-P[c] + 1 AICAR[c]
• With common name(s):
  • 1 phosphoribulosylformimino-AICAR-phosphate[c] + 1 L-glutamine[c] => 1 H+[c] + 1 L-glutamate[c] + 1 D-erythro-imidazole-glycerol-phosphate[c] + 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ19186
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ12953
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• HISTSYN-PWY, L-histidine biosynthesis: HISTSYN-PWY
  • 10 reactions found over 10 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 24793
• LIGAND-RXN:
  • R04558