RXN-11320

Reaction RXN-11320

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-1.14.11.29
• common name:
  • hypoxia-inducible factor-proline dioxygenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 HIF-Alpha[c] + 1 2-KETOGLUTARATE[c] + 1 OXYGEN-MOLECULE[c] => 1 4-hydroxy-L-proline-HIF-Alpha[c] + 1 SUC[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 a hypoxia inducible factor (HIF) α subunit[c] + 1 2-oxoglutarate[c] + 1 oxygen[c] => 1 a trans-4-hydroxy-L-proline-HIF α subunit[c] + 1 succinate[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ08884
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER

Reconstruction information

• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 48401