RXN-5464

Reaction RXN-5464

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-2.4.1.131
• common name:
  • DP-Man:Man3GlcNAc2-PP-dolichol α-1,2-mannosyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 GDP-MANNOSE[c] + 1 CPD-5162[c] => 1 CPD-5164[c] + 2 GDP[c] + 2 PROTON[c]
• With common name(s):
  • 2 GDP-α-D-mannose[c] + 1 α-D-Man-(1→3)-[α-D-Man-(1→6)]-α-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] => 1 α-D-Man-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] + 2 GDP[c] + 2 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ11238
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ05950
  • Source: orthology-ectocarpus_siliculosus

Pathways

• MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS, protein N-glycosylation initial phase (eukaryotic): MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
  • 16 reactions found over 19 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 29524