RXN-8665

Reaction RXN-8665

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-1.13.11.11
  • EC-1.13.11.52
• common name:
  • tryptophan 2,3-dioxygenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 TRP[c] + 1 OXYGEN-MOLECULE[c] => 1 N-FORMYLKYNURENINE[c]
• With common name(s):
  • 1 L-tryptophan[c] + 1 oxygen[c] => 1 N-formylkynurenine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ12575
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-5651, L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: PWY-5651
  • 3 reactions found over 5 reactions in the full pathway
• PWY-7717, 3-hydroxy-4-methyl-anthranilate biosynthesis I: PWY-7717
  • 3 reactions found over 6 reactions in the full pathway
• PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
  • 7 reactions found over 17 reactions in the full pathway
• TRPCAT-PWY, L-tryptophan degradation I (via anthranilate): TRPCAT-PWY
  • 2 reactions found over 3 reactions in the full pathway
• PWY-7765, 3-hydroxy-4-methyl-anthranilate biosynthesis II: PWY-7765
  • 3 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 24536
• LIGAND-RXN:
  • R00678
• UNIPROT:
  • P21643