RXN66-323

Reaction RXN66-323

• direction:
  • LEFT-TO-RIGHT
• common name:
  • cholesterol:NADP+ Δ7 -oxidoreductase
• ec number:
  • EC-1.3.1.21
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-4187[c] + 1 PROTON[c] + 1 NADPH[c] => 1 CHOLESTEROL[c] + 1 NADP[c]
• With common name(s):
  • 1 7-dehydrocholesterol[c] + 1 H+[c] + 1 NADPH[c] => 1 cholesterol[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ02661
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY66-341, cholesterol biosynthesis I: PWY66-341
  • 14 reactions found over 22 reactions in the full pathway
• PWY66-3, cholesterol biosynthesis II (via 24,25-dihydrolanosterol): PWY66-3
  • 12 reactions found over 22 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 23984
• LIGAND-RXN:
  • R01456