ACETOOHBUTREDUCTOISOM-RXN

Reaction ACETOOHBUTREDUCTOISOM-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 2-aceto-2-hydroxy-butyrate:NADPH+ oxidoreductase (isomerizing)
• ec number:
  • EC-1.1.1.86
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NADPH[c] + 1 2-ACETO-2-HYDROXY-BUTYRATE[c] + 1 PROTON[c] => 1 NADP[c] + 1 1-KETO-2-METHYLVALERATE[c]
• With common name(s):
  • 1 NADPH[c] + 1 (S)-2-aceto-2-hydroxybutanoate[c] + 1 H+[c] => 1 NADP+[c] + 1 (R)-2,3-dihydroxy-3-methylpentanoate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ10245
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-5103, L-isoleucine biosynthesis III: PWY-5103
  • 4 reactions found over 7 reactions in the full pathway
• ILEUSYN-PWY, L-isoleucine biosynthesis I (from threonine): ILEUSYN-PWY
  • 7 reactions found over 7 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 13493
• UNIPROT:
  • P06168
  • P44822
  • O25097
  • Q02138
  • Q57179
  • Q9JTI3
  • Q9PHN5
  • P05793
  • P38674
  • Q59500
  • Q01292
  • Q05758
  • O82043
  • P78827