RXN-5462

Reaction RXN-5462

• direction:
  • LEFT-TO-RIGHT
• common name:
  • GDP-Man:Man1GlcNAc2-PP-dolichol α-1,3-mannosyltransferase
• ec number:
  • EC-2.4.1.132
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ALPHA-D-MANNOSYLCHITOBIO[c] + 1 GDP-MANNOSE[c] => 1 CPD-5161[c] + 1 PROTON[c] + 1 GDP[c]
• With common name(s):
  • 1 β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] + 1 GDP-α-D-mannose[c] => 1 α-D-Man-(1→3)-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] + 1 H+[c] + 1 GDP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ17680
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS, protein N-glycosylation (eukaryotic, high mannose): MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
  • 19 reactions found over 19 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 29518
• LIGAND-RXN:
  • R05973
  • R05002