FORMATETHFLIG-RXN

Reaction FORMATETHFLIG-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • formate-tetrahydrofolate ligase
  • formate:tetrahydropteroylpolyglutamate ligase
• ec number:
  • EC-6.3.4.3
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ATP[c] + 1 FORMATE[c] + 1 THF-GLU-N[c] => 1 ADP[c] + 1 FORMYL-THF-GLU-N[c] + 1 Pi[c]
• With common name(s):
  • 1 ATP[c] + 1 formate[c] + 1 a tetrahydrofolate[c] => 1 ADP[c] + 1 an N10-formyl-tetrahydrofolate[c] + 1 phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ12991
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ07523
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• PWY-2201, folate transformations I: PWY-2201
  • 12 reactions found over 12 reactions in the full pathway
• PWY-2161, folate polyglutamylation: PWY-2161
  • 5 reactions found over 5 reactions in the full pathway
• PWY-1722, formate assimilation into 5,10-methylenetetrahydrofolate: PWY-1722
  • 3 reactions found over 3 reactions in the full pathway
• CODH-PWY, reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): CODH-PWY
  • 5 reactions found over 9 reactions in the full pathway
• PWY-3841, folate transformations II: PWY-3841
  • 10 reactions found over 11 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 20221
• LIGAND-RXN:
  • R00943
• UNIPROT:
  • P09440
  • P13419
  • P07245
  • P11586
  • P21164
  • P28723
  • Q9JVY8
  • Q9CH07
  • Q07064
  • Q27772